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全球精神障碍老年患者跌倒发生率的Meta 分析:观察性研究。

Worldwide prevalence of falls in older adults with psychiatric disorders: A meta-analysis of observational studies.

机构信息

Faculty of Health Sciences, Unit of Psychiatry, Institute of Translational Medicine, University of Macau, 3/F, Building E12, Macao SAR, China.

Faculty of Health Sciences, Unit of Psychiatry, Institute of Translational Medicine, University of Macau, 3/F, Building E12, Macao SAR, China; Department of Neurosurgery, the Affiliated Hospital of Southwest Medical University, Sichuan province, China.

出版信息

Psychiatry Res. 2019 Mar;273:114-120. doi: 10.1016/j.psychres.2018.12.165. Epub 2018 Dec 31.

DOI:10.1016/j.psychres.2018.12.165
PMID:30641340
Abstract

Falls are common in older adults with psychiatric disorders, but the epidemiological findings have been inconsistent. This meta-analysis examined the prevalence of falls in older psychiatric patients and its moderating factors. PubMed, EMBASE, Web of Science and PsycINFO databases were independently searched by three investigators from their inception date to Nov 31, 2017. The random effects meta-analysis was used to synthesize the prevalence of falls, while meta-regression and subgroup analyses were conducted to explore the moderating factors. Sixteen of the 2061 potentially relevant papers met the entry criteria for the meta-analysis. The pooled lifetime prevalence of falls was 17.25% (95% confidence interval: 13.14%-21.35%). Neither univariate and nor multivariate meta-regression analyses revealed any moderating effects of the study region, duration, sample size, and quality on the prevalence of falls (P values > 0.05). Falls in older adults with psychiatric disorders are common.

摘要

跌倒在患有精神疾病的老年人中很常见,但流行病学研究结果并不一致。本荟萃分析旨在调查老年精神科患者跌倒的发生率及其影响因素。从建库至 2017 年 11 月 31 日,3 位研究者分别独立检索了 PubMed、EMBASE、Web of Science 和 PsycINFO 数据库。采用随机效应荟萃分析综合跌倒发生率,同时进行荟萃回归和亚组分析以探讨影响因素。2061 篇潜在相关论文中有 16 篇符合荟萃分析的纳入标准。荟萃分析显示,终生跌倒发生率为 17.25%(95%置信区间:13.14%-21.35%)。无论是单变量还是多变量荟萃回归分析均未发现研究地区、持续时间、样本量和研究质量对跌倒发生率有调节作用(P 值均>0.05)。精神科老年患者跌倒很常见。

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