Brown S A
Department of Veterinary Physiology and Pharmacology, Texas Veterinary Medical Center, Texas A&M University College of Veterinary Medicine, College Station.
Vet Clin North Am Small Anim Pract. 1988 Nov;18(6):1197-216. doi: 10.1016/s0195-5616(88)50131-6.
This article includes an overview of the pathophysiology of seizures and a discussion of the mechanism of action of anticonvulsants based on the targeted physiologic processes. The commonly used anticonvulsants are classified and reviewed by chemical group. The concept, indications, and benefits of therapeutic monitoring of serum anticonvulsant concentrations are presented. The use of anticonvulsant agents for treatment of status epilepticus is addressed.
本文包括癫痫发作的病理生理学概述，以及基于靶向生理过程对抗惊厥药作用机制的讨论。常用的抗惊厥药按化学类别进行分类和综述。介绍了血清抗惊厥药浓度治疗监测的概念、适应证和益处。还讨论了抗惊厥药在癫痫持续状态治疗中的应用。
