Department of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan.
Department of Urology, Nishisaitama-chuo National Hospital, Saitama, Japan.
World J Urol. 2019 Apr;37(4):655-660. doi: 10.1007/s00345-019-02630-z. Epub 2019 Jan 14.
To report our experience with delayed anastomotic urethroplasty for pelvic fracture urethral injury (PFUI) during the last 10 years and evaluate both surgical and patient-reported outcomes.
Retrospective analysis of 115 patients undergoing delayed anastomotic urethroplasty for PFUI between 2008 and 2017 by a single surgeon (AH) was performed. Success was defined as a urethral lumen large enough for passage of a 17-Fr flexible cystoscope. We asked patients to complete questionnaires before (baseline) and 1 year after urethroplasty and compared by paired t and Wilcoxon signed-rank tests the answers to a question about LUTS-specific QOL and the health-related QOL indicated by EQ-5D index and visual analogue scores (EQVAS). Overall patient satisfaction 1 year after urethroplasty was also evaluated.
Urethroplasty was successful in 108 patients (93.9%), and failed urethroplasty was significantly associated with greater intraoperative blood loss (p = 0.009) and smaller surgical experience (p = 0.018). Sixty-six patients (57.4%) completed questionnaires 1 year after urethroplasty, and 65 of those 66 (98.5%) were "satisfied" (36.4%) or "very satisfied" (62.1%) with the outcome of their urethroplasty. The LUTS-specific QOL scores (p < 0.0001), EQ-5D index scores (p < 0.0001), and EQVAS scores (p < 0.0001) all improved significantly after urethroplasty.
Delayed anastomotic urethroplasty has a high success rate and significant beneficial effects on both LUTS-specific and health-related QOL, resulting in high patient satisfaction. Careful manipulation in a bloodless operative field by experienced surgeons could be the key to successful urethroplasty.
报告我们在过去 10 年中对骨盆骨折尿道损伤(PFUI)进行延迟吻合尿道成形术的经验,并评估手术和患者报告的结果。
对 2008 年至 2017 年间由一名外科医生(AH)进行的 115 例 PFUI 患者进行了延迟吻合尿道成形术的回顾性分析。成功定义为尿道内腔足以通过 17Fr 柔性膀胱镜。我们要求患者在尿道成形术前(基线)和术后 1 年完成问卷,并通过配对 t 检验和 Wilcoxon 符号秩检验比较对特定于 LUTS 的 QOL 和 EQ-5D 指数和视觉模拟评分(EQVAS)所示的健康相关 QOL 的回答。还评估了尿道成形术后 1 年的总体患者满意度。
108 例患者(93.9%)的尿道成形术成功,手术失功与术中出血量较大(p = 0.009)和手术经验较小(p = 0.018)显著相关。66 例患者(57.4%)在尿道成形术后 1 年完成了问卷,其中 65 例(98.5%)对其尿道成形术的结果“满意”(36.4%)或“非常满意”(62.1%)。尿道成形术后,LUTS 特定的 QOL 评分(p<0.0001)、EQ-5D 指数评分(p<0.0001)和 EQVAS 评分(p<0.0001)均显著改善。
延迟吻合尿道成形术成功率高,对 LUTS 特异性和健康相关 QOL 均有显著有益影响,患者满意度高。经验丰富的外科医生在无血手术野中进行精细操作可能是成功尿道成形术的关键。