State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, P. R. China.
Collaborative Innovation Center of Chemistry for Energy Materials, Xiamen University, Xiamen, 361005, P. R. China.
Angew Chem Int Ed Engl. 2019 Mar 18;58(12):3967-3971. doi: 10.1002/anie.201814752. Epub 2019 Feb 7.
Chemical detection has a wide range of applications. The detection of a certain substance is so vital that new detection mechanisms with features such as low-cost, accessibility, and readily available visual markers are in demand. Herein, a liquid-gating-based chemical-detection mechanism is reported, which has a dynamic gas/liquid interface due to dipole-induced interfacial molecular reconfiguration. The mechanism exhibits a sensitive relationship between the dipole-force-induced rearrangement of interfacial molecules and transmembrane gating behavior. These features can be utilized to create visual markers for detection by converting the analyte-mediated interfacial interaction to a pressure-driven marker movement. This "green" detection mechanism requires no electrical energy input and has readily available markers for anyone to observe directly. This new mechanism opens a window for a more in-depth exploration of combining liquid-gating mechanisms with detection mechanisms.
化学检测具有广泛的应用。对某种物质的检测至关重要，因此需要具有低成本、易获取和易于获得可视标记等特点的新型检测机制。本文报道了一种基于液门的化学检测机制，由于偶极力诱导的界面分子重排，该机制具有动态的气/液界面。该机制表现出界面分子偶极力诱导重排与跨膜门控行为之间的敏感关系。这些特性可用于通过将分析物介导的界面相互作用转换为压力驱动的标记运动来创建用于检测的可视标记。这种“绿色”检测机制不需要电能输入，并且任何人均可直接使用易于获得的标记进行直接观察。这种新机制为更深入地探索将液门机制与检测机制相结合开辟了道路。
