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甲状腺髓外造血的细胞诊断揭示一种无症状血液系统恶性肿瘤。

Cytodiagnosis of extramedullary hematopoiesis in thyroid gland unravelling an asymptomatic hematological malignancy.

作者信息

Kishore Manjari, Kaushal Manju, Marwah Sadhna, Sharma Megha, Sharma Nishi, Mittal Vishakha

机构信息

Department of Pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Department of ENT, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

出版信息

Diagn Cytopathol. 2019 Apr;47(4):320-324. doi: 10.1002/dc.24082. Epub 2019 Jan 15.

DOI:10.1002/dc.24082
PMID:30644655
Abstract

Extramedullary hematopoeisis (EMH), also known as myeloid metaplasia can be seen in association with various hematological disorders. The common sites of EMH are liver, spleen and lymph nodes; but it can occur in almost any organ and in numerous locations. Involvement of the thyroid gland with EMH has rarely been reported. We present a case of EMH in the thyroid gland in an adult female diagnosed on fine-needle aspiration cytology (FNAC) which further helped in revealing an underlying myeloproliferative neoplasm; chronic myeloid leukemia (CML).

摘要

髓外造血(EMH),也称为髓样化生,可见于多种血液系统疾病。EMH的常见部位是肝脏、脾脏和淋巴结;但它几乎可发生于任何器官及众多部位。甲状腺受累于EMH的情况鲜有报道。我们报告一例成年女性甲状腺EMH病例,通过细针穿刺抽吸活检(FNAC)确诊,这进一步有助于揭示潜在的骨髓增殖性肿瘤;慢性粒细胞白血病(CML)。

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