Ozturk O, Koklu H, Akbal E, Aksoy E K, Altan E, Basar O, Yuksel O, Arslan S, Koklu S
Department of Gastroenterology, Hacettepe University School of Medicine, Ankara, Turkey.
Department of Gastroenterology, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.
Acta Gastroenterol Belg. 2018 Oct-Dec;81(4):490-495.
Although several factors are thought to be responsible for the development of colonic diverticulosis (CD), the underlying pathogenesis is still obscure and needs clarification. The aim of this study was to determine the prevalence, location and clinical features of CD and especially to detect whether there is an association between CD and postures during defecation.
This prospective study enrolled 757 patients. The subjects were divided into two groups as a diverticulosis group (D group, n:95) and non-diverticulosis group (non-D group, n:662).
The median patient age was 54.9±13.2 years. CD frequency was 12.5% (n:95). The most commonly involved part of the colon was the sigmoid colon (56.8%). Diverticula location was on the left in 45.3% (n:43), on the right in 24.2% (n:23) and on both sides of the colon in 30.5% (n:29). Patients in the D group were older (p<0.001) and were predominantly female (p:0.04). The frequency of sitting during defecation (Western type toilet) was higher in the D group compared to the non-D group (72.2% vs 53.5%; p:0.007). The use-time of a Western-type toilet was longer in the D group compared to the non-D group (p:0.04). In multivariable logistic regression analysis, age and toilet type were independent risk factors for the development of diverticulosis.
Sitting during defecation seems to increase the risk of CD.
尽管多种因素被认为与结肠憩室病（CD）的发生有关，但其潜在发病机制仍不明确，需要进一步阐明。本研究旨在确定CD的患病率、部位及临床特征，尤其要探究CD与排便姿势之间是否存在关联。
本前瞻性研究纳入了757例患者。研究对象被分为两组，即憩室病组（D组，n = 95）和非憩室病组（非D组，n = 662）。
患者的中位年龄为54.9±13.2岁。CD的发生率为12.5%（n = 95）。结肠最常受累的部位是乙状结肠（56.8%）。憩室位于左侧的占45.3%（n = 43），位于右侧的占24.2%（n = 23），双侧均有的占30.5%（n = 29）。D组患者年龄较大（p<0.001），且以女性为主（p = 0.04）。与非D组相比，D组排便时坐着（使用西式马桶）的频率更高（72.2%对53.5%；p = 0.007）。D组使用西式马桶的时间比非D组更长（p = 0.04）。在多变量逻辑回归分析中，年龄和马桶类型是憩室病发生的独立危险因素。
排便时坐着似乎会增加患CD的风险。
