Jiang Rong-San, Wang Jing-Jie
Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan.
Int J Otolaryngol. 2018 Dec 17;2018:6270614. doi: 10.1155/2018/6270614. eCollection 2018.
The effect of red light rhinophototherapy (RLRPT) on nasal patency in patients with a clinical diagnosis of allergic rhinitis was investigated.
Subjects were randomly divided into 2 groups, with patients in one group given one treatment session of RLRPT, followed by medical treatment. Those in the second group were treated with medical treatment only. The rhinitis symptoms were evaluated both before and 30 minutes after RLRPT and 2 days later. The nasal patency was objectively measured through the use of both active anterior rhinomanometry and acoustic rhinometry before and 30 minutes after RLRPT.
All rhinitis symptoms, including nasal congestion, significantly improved 30 minutes after a single RLRPT treatment, but worsened again, particularly for sneezing, 2 days later. Nasal resistance slightly decreased 30 minutes after RLRPT. The first minimal cross-sectional area did not change after RLRPT, but the second minimal cross-sectional area with the volume of the nasal cavity between 2.0 and 5.0 cm from the tip of the nosepiece significantly lessened.
This study showed that RLRPL did not objectively improve patient's nasal patency.
The trial is registered with NCT03752645.
研究红光鼻腔光疗（RLRPT）对临床诊断为变应性鼻炎患者鼻腔通畅度的影响。
将受试者随机分为两组，一组患者接受一次RLRPT治疗，随后进行药物治疗。另一组仅接受药物治疗。在RLRPT治疗前、治疗后30分钟和2天后评估鼻炎症状。在RLRPT治疗前和治疗后30分钟，通过主动前鼻测压法和鼻声反射法客观测量鼻腔通畅度。
单次RLRPT治疗30分钟后，包括鼻塞在内的所有鼻炎症状均显著改善，但2天后症状再次恶化，尤其是打喷嚏症状。RLRPT治疗30分钟后鼻阻力略有下降。RLRPT治疗后第一个最小横截面积未发生变化，但在距鼻探头尖端2.0至5.0厘米处鼻腔容积对应的第二个最小横截面积显著减小。
本研究表明，RLRPL并未客观改善患者的鼻腔通畅度。
该试验已在NCT03752645注册。
