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Cell-surface GPNMB and induction of stemness.

作者信息

Okita Yukari, Chen Chen, Kato Mitsuyasu

机构信息

Yukari Okita: Department of Experimental Pathology, Faculty of Medicine; Division of Cell Dynamics, Transborder Medical Research Center, University of Tsukuba, Ibaraki, Japan.

出版信息

Oncotarget. 2018 Dec 18;9(99):37289-37290. doi: 10.18632/oncotarget.26472.

DOI:10.18632/oncotarget.26472
PMID:30647869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6324665/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ce/6324665/dd47fd225e37/oncotarget-09-37289-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ce/6324665/dd47fd225e37/oncotarget-09-37289-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ce/6324665/dd47fd225e37/oncotarget-09-37289-g001.jpg

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本文引用的文献

1
Glycoprotein nmb Is Exposed on the Surface of Dormant Breast Cancer Cells and Induces Stem Cell-like Properties.糖蛋白 nmb 暴露于休眠乳腺癌细胞表面并诱导干细胞样特性。
Cancer Res. 2018 Nov 15;78(22):6424-6435. doi: 10.1158/0008-5472.CAN-18-0599. Epub 2018 Sep 17.
2
Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB) and Cancer: A Novel Potential Therapeutic Target.糖蛋白非转移性黑色素瘤蛋白B(GPNMB)与癌症:一种新型潜在治疗靶点。
Steroids. 2018 May;133:102-107. doi: 10.1016/j.steroids.2017.10.013. Epub 2017 Oct 31.
3
Concise Review: Stem Cells and Epithelial-Mesenchymal Transition in Cancer: Biological Implications and Therapeutic Targets.
头颈部鳞状细胞癌中 GPNMB 阳性细胞——其在癌症干性、治疗抵抗和转移中的作用。
Pathol Oncol Res. 2022 Aug 19;28:1610450. doi: 10.3389/pore.2022.1610450. eCollection 2022.
4
GPNMB: a potent inducer of immunosuppression in cancer.GPNMB:癌症中具有强大免疫抑制作用的诱导剂。
Oncogene. 2022 Oct;41(41):4573-4590. doi: 10.1038/s41388-022-02443-2. Epub 2022 Sep 1.
5
Glycoprotein non-metastatic melanoma protein B functions with growth factor signaling to induce tumorigenesis through its serine phosphorylation.糖蛋白非转移性黑色素瘤蛋白B通过其丝氨酸磷酸化与生长因子信号传导共同作用,诱导肿瘤发生。
Cancer Sci. 2021 Oct;112(10):4187-4197. doi: 10.1111/cas.15090. Epub 2021 Aug 10.
简要综述:癌症中的干细胞与上皮-间质转化:生物学意义及治疗靶点
Stem Cells. 2016 Aug;34(8):1997-2007. doi: 10.1002/stem.2406. Epub 2016 Jun 20.
4
Glycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer.糖蛋白非转移性 b(GPNMB):癌症中的转移介质和新兴治疗靶点。
Onco Targets Ther. 2013 Jul 9;6:839-52. doi: 10.2147/OTT.S44906. Print 2013.
5
Transforming growth factor-β induces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.转化生长因子-β诱导转录因子 MafK 和 Bach1 抑制血红素加氧酶-1 基因的表达。
J Biol Chem. 2013 Jul 12;288(28):20658-67. doi: 10.1074/jbc.M113.450478. Epub 2013 Jun 4.
6
Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression.上皮-间充质转化和癌症干细胞:乳腺癌进展中的危险动态双因素。
Breast Cancer Res. 2011 Feb 8;13(1):202. doi: 10.1186/bcr2789.
7
The basics of epithelial-mesenchymal transition.上皮-间质转化的基础知识。
J Clin Invest. 2009 Jun;119(6):1420-8. doi: 10.1172/JCI39104.
8
The epithelial-mesenchymal transition generates cells with properties of stem cells.上皮-间质转化产生具有干细胞特性的细胞。
Cell. 2008 May 16;133(4):704-15. doi: 10.1016/j.cell.2008.03.027.
9
Prospective identification of tumorigenic breast cancer cells.致瘤性乳腺癌细胞的前瞻性鉴定。
Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3983-8. doi: 10.1073/pnas.0530291100. Epub 2003 Mar 10.