• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

伴有微乳头成分的胃癌组织病理学参数研究

Study of Histopatological Parameters of Gastric Carcinomas with Micropapillary Component.

作者信息

Dobrițoiu M, Stepan A E, Vere C C, Cataraga I, Simionescu C E

机构信息

PhD student, University of Medicine and Pharmacy of Craiova.

Department of Pathology, University of Medicine and Pharmacy of Craiova.

出版信息

Curr Health Sci J. 2018 Jul-Sep;44(3):225-230. doi: 10.12865/CHSJ.44.03.04. Epub 2018 Jul 15.

DOI:10.12865/CHSJ.44.03.04
PMID:30647941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6311226/
Abstract

Micropapillary carcinoma was recently identified as a carcinoma variant characterized by the presence of small clusters of tumor cells located in optically empty spaces. The study included a number of 14 cases represented by surgical excision specimens diagnosed with gastric carcinoma (tubular, papillary and signet-ring) which associated the micropapillary component in variable proportions. Regarding the low-grade tubular carcinomas, the micropapillary component represented less than 25% of the tumor, while in the high-grade tubular carcinomas and papillary carcinomas it represented 25-50%. Among signet-ring carcinomas, the micropapillary component had a percentage of over 50. The depth of invasion was frequently associated with T3 and T4 categories. Lymph nodes metastasis were found in ten cases and distant metastasis were present in three cases. Recognition of the micropapillary component associated with gastric carcinoma represents an aspect of great importance because it is frequently correlated with unfavorable prognosis parameters.

摘要

微乳头癌最近被确认为一种癌变体，其特征是在光学上呈空泡状的区域存在小簇肿瘤细胞。该研究纳入了14例经手术切除标本诊断为胃癌（管状、乳头状和印戒细胞型）的病例，这些病例中微乳头成分所占比例各不相同。对于低级别管状癌，微乳头成分占肿瘤的比例不到25%，而在高级别管状癌和乳头状癌中，其占比为25%-50%。在印戒细胞癌中，微乳头成分的占比超过50%。浸润深度常与T3和T4分期相关。10例出现淋巴结转移，3例出现远处转移。认识到与胃癌相关的微乳头成分是一个非常重要的方面，因为它常常与不良预后参数相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/67d20656787e/CHSJ-44-03-04-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/8c4804acb7f1/CHSJ-44-03-04-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/719b00457385/CHSJ-44-03-04-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/7021d6795228/CHSJ-44-03-04-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/0ea393eed85f/CHSJ-44-03-04-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/6c204278a82e/CHSJ-44-03-04-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/67d20656787e/CHSJ-44-03-04-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/8c4804acb7f1/CHSJ-44-03-04-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/719b00457385/CHSJ-44-03-04-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/7021d6795228/CHSJ-44-03-04-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/0ea393eed85f/CHSJ-44-03-04-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/6c204278a82e/CHSJ-44-03-04-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d4/6311226/67d20656787e/CHSJ-44-03-04-fig6.jpg

相似文献

1
Study of Histopatological Parameters of Gastric Carcinomas with Micropapillary Component.伴有微乳头成分的胃癌组织病理学参数研究
Curr Health Sci J. 2018 Jul-Sep;44(3):225-230. doi: 10.12865/CHSJ.44.03.04. Epub 2018 Jul 15.
2
Phagocytosis (cannibalism) of apoptotic neutrophils by tumor cells in gastric micropapillary carcinomas.胃微乳头癌中肿瘤细胞对凋亡中性粒细胞的吞噬作用（同类相食）
World J Gastroenterol. 2015 May 14;21(18):5548-54. doi: 10.3748/wjg.v21.i18.5548.
3
Colorectal adenocarcinoma with micropapillary pattern and its association with lymph node metastasis.具有微乳头结构的结直肠癌及其与淋巴结转移的关系。
Mod Pathol. 2007 Jul;20(7):729-33. doi: 10.1038/modpathol.3800790. Epub 2007 Apr 27.
4
[A rare case of colorectal micropapillary carcinoma].
Gac Med Mex. 2011 Sep-Oct;147(5):432-6.
5
Micropapillary early gastric carcinoma with distinct clinicopathological features, high risk for lymph node metastasis, and dismal prognosis: a multicenter clinicopathological study of 29 cases identified in 1890 early gastric carcinoma radical gastrectomies.具有明显临床病理特征、高淋巴结转移风险和预后不良的微乳头状早期胃癌：1890 例早期胃癌根治性胃切除术中发现的 29 例多中心临床病理研究。
Hum Pathol. 2019 Jan;83:149-158. doi: 10.1016/j.humpath.2018.08.023. Epub 2018 Sep 1.
6
Gastric cancer: correlation between clinicopathological factors and survival of patients. II.胃癌：临床病理因素与患者生存率的相关性。II.
Rom J Morphol Embryol. 2009;50(2):185-94.
7
Mucinous micropapillary carcinoma of the breast: an aggressive counterpart to conventional pure mucinous tumors.乳腺黏液性微乳头状癌：一种比传统纯黏液性肿瘤更具侵袭性的对应物。
Hum Pathol. 2013 Aug;44(8):1577-85. doi: 10.1016/j.humpath.2013.01.003. Epub 2013 Mar 19.
8
Micropapillary variant of transitional cell carcinoma of the ureter.输尿管移行细胞癌的微乳头变异型
Pathol Int. 2000 Jan;50(1):52-6. doi: 10.1046/j.1440-1827.2000.00997.x.
9
Invasive micropapillary carcinoma of the breast metastatic to the urinary bladder and endometrium: diagnostic pitfalls and review of the literature of tumors with micropapillary features.乳腺浸润性微乳头状癌转移至膀胱和子宫内膜：诊断陷阱及具有微乳头特征肿瘤的文献综述
Ann Diagn Pathol. 2003 Apr;7(2):112-9. doi: 10.1053/adpa.2003.50015.
10
Invasive micropapillary urothelial carcinoma of the bladder.膀胱浸润性微乳头状尿路上皮癌。
Hum Pathol. 2010 Aug;41(8):1159-64. doi: 10.1016/j.humpath.2009.11.018. Epub 2010 Apr 8.

本文引用的文献

1
Invasive micropapillary carcinoma: a distinct type of adenocarcinomas in the gastrointestinal tract.浸润性微乳头状癌：胃肠道腺癌的一种独特类型。
World J Gastroenterol. 2014 Apr 28;20(16):4597-606. doi: 10.3748/wjg.v20.i16.4597.
2
Gastric carcinoma with invasive micropapillary pattern and its association with lymph node metastasis.胃浸润性微乳头状癌及其与淋巴结转移的关系。
Histopathology. 2011 Dec;59(6):1081-9. doi: 10.1111/j.1365-2559.2011.04055.x.
3
Clinicopathological features of stomach cancer with invasive micropapillary component.
具有浸润性微乳头状成分的胃癌的临床病理特征。
Gastric Cancer. 2012 Apr;15(2):179-87. doi: 10.1007/s10120-011-0094-5. Epub 2011 Oct 12.
4
Gastric micropapillary carcinoma: A distinct subtype with a significantly worse prognosis in TNM stages I and II.胃微乳头状癌：在 TNM Ⅰ期和Ⅱ期中具有明显更差预后的独特亚型。
Am J Surg Pathol. 2011 Jan;35(1):84-91. doi: 10.1097/PAS.0b013e3181ff61e2.
5
Micropapillary carcinoma of stomach: a clinicopathologic and immunohistochemical study of 11 cases.胃微乳头状癌：11 例临床病理及免疫组化研究。
Am J Surg Pathol. 2010 Aug;34(8):1139-46. doi: 10.1097/PAS.0b013e3181e7043b.
6
Primary invasive micropapillary carcinoma of the stomach.原发性胃浸润性微乳头状癌
Pathol Int. 2008 Aug;58(8):513-7. doi: 10.1111/j.1440-1827.2008.02265.x.
7
Serous papillary adenocarcinoma of the female genital organs and invasive micropapillary carcinoma of the breast. Are WT1, CA125, and GCDFP-15 useful in differential diagnosis?女性生殖器官浆液性乳头状腺癌及乳腺浸润性微乳头状癌。WT1、CA125和GCDFP - 15在鉴别诊断中有用吗？
Hum Pathol. 2008 May;39(5):666-71. doi: 10.1016/j.humpath.2007.09.009. Epub 2008 Mar 12.
8
Gastric remnant adenocarcinoma with micropapillary component.伴有微乳头成分的残胃癌
Dig Dis Sci. 2008 Aug;53(8):2287-9. doi: 10.1007/s10620-007-0136-3. Epub 2008 Jan 26.
9
Primary invasive micropapillary carcinoma of the colon.原发性结肠浸润性微乳头癌。
Histopathology. 2005 Nov;47(5):479-84. doi: 10.1111/j.1365-2559.2005.02241.x.
10
Carcinomas with micropapillary morphology: clinical significance and current concepts.具有微乳头形态的癌：临床意义及当前概念
Adv Anat Pathol. 2004 Nov;11(6):297-303. doi: 10.1097/01.pap.0000138142.26882.fe.