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厄他培南在治疗培养结果为阳性的复杂性腹腔内感染中的作用

The Role of Ertapenem for the Treatment of Complicated Intra-abdominal Infections With a Positive Culture for .

作者信息

Fabre Valeria, Nemati Koorosh, Avdic Edina, Cosgrove Sara E, Amoah Joe, Tamma Pranita D

机构信息

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

Open Forum Infect Dis. 2018 Dec 15;6(1):ofy339. doi: 10.1093/ofid/ofy339. eCollection 2019 Jan.

Abstract

Controversy remains as to whether recovered from intra-abdominal infections (IAIs) requires targeted therapy. In a multicenter study comparing patients with IAIs from which was identified in intra-abdominal cultures, no difference in clinical outcomes was observed between patients receiving ertapenem vs those receiving piperacillin/tazobactam.

摘要

对于从腹腔内感染(IAIs)中康复的患者是否需要靶向治疗仍存在争议。在一项多中心研究中,比较了腹腔内培养物中鉴定出[病原体]的IAIs患者,接受厄他培南治疗的患者与接受哌拉西林/他唑巴坦治疗的患者在临床结局上未观察到差异。

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本文引用的文献

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Bactericidal activity of ertapenem against major intra-abdominal pathogens.厄他培南对主要腹腔内病原体的杀菌活性。
Int J Antimicrob Agents. 2006 Nov;28(5):396-401. doi: 10.1016/j.ijantimicag.2006.07.018. Epub 2006 Oct 11.
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Properties and potential of ertapenem.厄他培南的特性与潜力。
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