Valente C, Fruganti G, Tesei B, Ciorba A, Cardaras P, Floris A, Bordoni E
Cattedra di Patologia e Profilassi delle Malattie Infettive, Università di Perugia, Italy.
Comp Immunol Microbiol Infect Dis. 1988;11(3-4):189-98. doi: 10.1016/0147-9571(88)90037-9.
The immune response to the K99 was tested in 45 pregnant cows, subcutaneously vaccinated, for protecting the newborn calves. Serological tests were performed in the blood sera of all animals and in the milk and colostrum sera; hemogram, inhibition of the adhesion to the brush border and histological tests were performed. The calves from vaccinated cows survived the experimental infection after the suction of colostrum in spite of the fact that the calves from control dams died with diarrhea.
对45头怀孕母牛进行皮下接种，以测试其对K99的免疫反应，目的是保护新生小牛。对所有动物的血清、牛奶和初乳血清进行了血清学检测；进行了血常规、对刷状缘粘附的抑制试验和组织学检测。尽管对照母牛所生小牛死于腹泻，但接种母牛所生小牛在吸食初乳后在实验性感染中存活下来。
