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采用 Bahasa 版本的 EQ-5D 量表评估印度尼西亚 2 型糖尿病门诊患者的健康相关生活质量。

Health-related quality of life in Indonesian type 2 diabetes mellitus outpatients measured with the Bahasa version of EQ-5D.

机构信息

Unit of Pharmacotherapy, Epidemiology & Economics (PTE2), Department of Pharmacy, Faculty of Science and Engineering (FSE), University of Groningen, Groningen, The Netherlands.

Banggai Laut Public Hospital, Banggai Laut Local Government, Central Sulawesi, Indonesia.

出版信息

Qual Life Res. 2019 May;28(5):1179-1190. doi: 10.1007/s11136-019-02105-z. Epub 2019 Jan 16.

Abstract

OBJECTIVES

To present EuroQol-5D (EQ-5D) index scores in Indonesian type 2 diabetes mellitus (T2DM) outpatients and to investigate the associations between EQ-5D and socio-demographic characteristics and clinical condition.

METHODS

Socio-demographic data were collected by interviewing participants, clinical data were obtained from treating physicians and self-reporting. Participants originated from primary and secondary care facilities in the Java and Sulawesi regions. Ordinal regression analysis was conducted with the quintiles of the EQ-5D index scores as the dependent variable to investigate the multivariate association with the participants' socio-demographic characteristics and clinical condition.

RESULTS

907 participants completed the five-level Indonesian version of the EQ-5D. The mean age of the participants was 59.3 (SD 9.7), and 57% were female. The overall EQ-5D index score was 0.77 (0.75-0.79). Male participants had a higher EQ-5D index score compared to females, and the highest percentage of self-reported health problems was in the pain/discomfort dimension (61%). Factors identified as being significantly associated with lower EQ-5D index scores were: (i) treatment in secondary care, (ii) lower educational level, (iii) dependency on caregivers, (iv) not undergoing T2DM therapy, and (v) being a housewife.

CONCLUSION

This study provides estimates of EQ-5D index scores that can be used in health economic evaluations. As housewives were found to experience more T2DM-related pain/discomfort and anxiety/depression, targeted approaches to reduce these problems should be aimed specifically at this group of patients. Potential approaches could involve disease-specific-counselors (health literacy partners) who provide routine monitoring of T2DM therapy as well as improved health promotion among T2DM communities.

摘要

目的

呈现印尼 2 型糖尿病(T2DM)门诊患者的欧洲五维健康量表(EQ-5D)指数评分,并探讨 EQ-5D 与社会人口统计学特征和临床状况之间的关系。

方法

通过访谈参与者收集社会人口统计学数据,从初级和二级保健机构的治疗医生和自我报告中获取临床数据。参与者来自爪哇和苏拉威西地区的初级和二级保健机构。采用有序回归分析,将 EQ-5D 指数评分的五分位数作为因变量,探讨与参与者社会人口统计学特征和临床状况的多变量关联。

结果

907 名参与者完成了五水平印尼版 EQ-5D。参与者的平均年龄为 59.3(SD 9.7),57%为女性。总体 EQ-5D 指数评分为 0.77(0.75-0.79)。男性参与者的 EQ-5D 指数评分高于女性,自我报告的健康问题比例最高的是疼痛/不适维度(61%)。与 EQ-5D 指数评分较低显著相关的因素包括:(i)在二级保健接受治疗,(ii)教育程度较低,(iii)依赖护理人员,(iv)未接受 T2DM 治疗,以及(v)是家庭主妇。

结论

本研究提供了可用于健康经济评估的 EQ-5D 指数评分估计值。由于家庭主妇被发现经历更多与 T2DM 相关的疼痛/不适和焦虑/抑郁,因此应针对这一特定患者群体采取有针对性的方法来解决这些问题。潜在的方法可能包括疾病特异性顾问(健康素养伙伴),他们对 T2DM 治疗进行常规监测,并在 T2DM 社区中开展更好的健康促进工作。

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