Proglucagon-derived peptides: nomenclature, biosynthetic relationships and physiological roles.

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作者信息

Conlon J M

机构信息

Clinical Research Group for Gastrointestinal Endocrinology, Max-Planck-Gesellschaft, University of Göttingen, FRG.

出版信息

Diabetologia. 1988 Aug;31(8):563-6. doi: 10.1007/BF00264761.

DOI:10.1007/BF00264761

PMID:3065110

Abstract

摘要

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Purification and chemical characterization of a glicentin-related pancreatic peptide (proglucagon fragment) from porcine pancreas.从猪胰腺中纯化和化学表征一种胰高血糖素相关胰肽（胰高血糖素原片段）

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Glicentin inhibits gastric acid secretion in the rat.胰高血糖素样肽抑制大鼠胃酸分泌。

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Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem.胰高血糖素原前体 cDNA 包含两个串联排列的与胰高血糖素相关的编码序列。

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Annu Rev Physiol. 1982;44:625-38. doi: 10.1146/annurev.ph.44.030182.003205.

The primary structure of porcine glicentin (proglucagon).猪胰高血糖素原（胰高血糖素原）的一级结构。

Regul Pept. 1981 May;2(2):139-50. doi: 10.1016/0167-0115(81)90007-0.

The glucagon-like polypeptides - order out of chaos?

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Nature. 1983;304(5924):368-71. doi: 10.1038/304368a0.

Hamster preproglucagon contains the sequence of glucagon and two related peptides.仓鼠前胰高血糖素原包含胰高血糖素的序列以及两种相关肽。

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Mammalian pancreatic preproglucagon contains three glucagon-related peptides.

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