Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
J Clin Microbiol. 2019 Mar 28;57(4). doi: 10.1128/JCM.01890-18. Print 2019 Apr.
To determine if rapid molecular testing for respiratory viruses in patients with respiratory illnesses can provide advantages to patients and hospitals, rigorous investigations on the impacts of using these assays are required. Well-conducted studies are needed to inform decisions about implementation of new rapid assays to replace standard molecular testing or to initiate testing in laboratories that are currently not doing molecular tests for respiratory viruses due to the complex nature of standard panels. In this issue of the , N. Wabe et al. (J Clin Microbiol 57:e01727-18, 2019, https://doi.org/10.1128/JCM.01727-18) report the results of their evaluation of the impact of using a rapid molecular test for influenza A/influenza B and RSV on outcomes for adults hospitalized with respiratory illness. The median time from admission to test result of the rapid test was 7.5 h compared to 40.3 h for the standard PCR assay. Compared to the use of the standard molecular assay, use of a rapid test significantly shortened time in the hospital and reduced the number of other microbiology tests performed. The authors concluded that rapid PCR testing of adults hospitalized with respiratory illnesses could provide benefits to both the patients and the hospital. Patients were able to leave the hospital earlier and a greater proportion of them had received their test results before discharge, which would allow appropriate treatment to be provided more quickly.
为了确定在患有呼吸道疾病的患者中快速进行呼吸道病毒分子检测是否对患者和医院有利,需要对这些检测的影响进行严格的调查。需要进行精心设计的研究,以便为有关实施新的快速检测以替代标准分子检测或在目前由于标准检测板的复杂性而未对呼吸道病毒进行分子检测的实验室启动检测的决策提供信息。在本期《临床微生物学杂志》上,N. Wabe 等人(J Clin Microbiol 57:e01727-18, 2019, https://doi.org/10.1128/JCM.01727-18)报告了他们评估使用快速流感 A/流感 B 和 RSV 分子检测对因呼吸道疾病住院的成年人的影响的结果。与标准 PCR 检测相比,快速检测的入院至检测结果的中位数时间为 7.5 小时,而标准 PCR 检测为 40.3 小时。与使用标准分子检测相比,使用快速检测可显著缩短住院时间并减少进行的其他微生物学检测次数。作者得出结论,对因呼吸道疾病住院的成年人进行快速 PCR 检测可能对患者和医院都有好处。患者能够更早出院,并且有更大比例的患者在出院前收到了检测结果,这可以使他们更快地接受适当的治疗。