Meier M S, Schmidt-Kessen W
MMW Munch Med Wochenschr. 1978 Mar 17;120(11):357-62.
The blood serum fasting levels of inorganic sulfate increase with age, other differences are largely due to diet. The serum sulfate shows a circadian rhythm with a minimum before noon and a maximum in the afternoon and evening. Urinary excretion of sulfate disappears during a low-protein diet. The serum sulfate levels rise temporarily if oral intake of protein, water or inorganic sulfate in non-laxative doses is increased. From the decomposition of protein, sulfate is first excreted with alkali cations and sooner than other catabolites. Drinking water mobilizes sulfate from its tissue pool, which can be blocked by the addition of sodium chloride. The subsequent excretion of an oral sulfate dose is prolonged over one day.
血清中无机硫酸盐的空腹水平随年龄增长而升高,其他差异主要归因于饮食。血清硫酸盐呈现昼夜节律,中午前最低,下午和晚上最高。低蛋白饮食期间,硫酸盐的尿排泄消失。如果非泻药剂量的蛋白质、水或无机硫酸盐的口服摄入量增加,血清硫酸盐水平会暂时升高。从蛋白质分解过程中,硫酸盐首先与碱金属阳离子一起排泄,且比其他分解代谢产物排泄得更早。饮用水会从组织库中调动硫酸盐,而添加氯化钠可阻止这种调动。口服硫酸盐剂量后的后续排泄会持续一天以上。