Vanishree M, Manvikar Vardendra, Rudraraju Amrutha, Reddy K M Parveen, Kumar N H Praveen, Quadri Syed Jaffar M
Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital, Raichur, Karnataka, India.
Department of Pedodontics, Navodaya Dental College and Hospital, Raichur, Karnataka, India.
J Oral Maxillofac Pathol. 2018 Sep-Dec;22(3):448. doi: 10.4103/jomfp.JOMFP_201_18.
The present study was designed to evaluate the frequency of micronuclei (MN) in the buccal exfoliated cells of mobile phone users. In addition, comparison of MN frequency between high and low mobile phone users was also done.
A total of 30 male and 30 female participants between the age group of 20-28 years were selected from the Outpatient Department of Navodaya Dental College and Hospital, Raichur, Karnataka. The participants were divided into two groups: Group A - low mobile phone users and Group B - high mobile phone users. Cell sampling and preparation was done on the slide. All the slides were observed for a total of 1000 cells for the presence and number of MN in each cell.
There was a significant increase in the mean MN count in Group B in comparison to the Group A. There was highly significant difference in the mean MN count of participants using (code division multiple access) CDMA than (global system for mobiles) GSM mobile phones. The MN mean count was found to be significantly increased in nonheadphone users in comparison to headphone users. In Group B, the MN count on the side of mobile phone use was found to be statistically significantly elevated in comparison to the opposite side.
Mobile phone radiation even in the permissible range when used for longer duration can cause significant genotoxicity. The genotoxicity accentuates when mobile phones are frequently used on the same side which may be due to more amount of radiation and increase in the temperature. Headphone usage reduces the genotoxicity of mobile phone radiation to some extent.
本研究旨在评估手机使用者颊部脱落细胞中微核（MN）的频率。此外，还对高手机使用量和低手机使用量人群的微核频率进行了比较。
从卡纳塔克邦赖丘尔市纳沃代亚牙科学院和医院门诊部选取了30名年龄在20 - 28岁之间的男性和30名女性参与者。参与者被分为两组：A组 - 低手机使用量人群和B组 - 高手机使用量人群。在载玻片上进行细胞采样和制备。观察所有载玻片上的1000个细胞，统计每个细胞中微核的存在情况和数量。
与A组相比，B组的平均微核计数显著增加。使用码分多址（CDMA）手机的参与者的平均微核计数与使用全球移动通信系统（GSM）手机的参与者相比存在极显著差异。与使用耳机的用户相比，未使用耳机的用户的微核平均计数显著增加。在B组中，发现使用手机一侧的微核计数与另一侧相比在统计学上显著升高。
即使在允许范围内，长时间使用手机辐射也会导致显著的遗传毒性。当手机经常在同一侧使用时，遗传毒性会加剧，这可能是由于辐射量增加和温度升高所致。使用耳机在一定程度上降低了手机辐射的遗传毒性。
