一种免疫快速疟原虫Pf/Pv快速诊断试验在巴西西部亚马逊地区用于疟疾诊断的性能。
Performance of an immuno-rapid malaria Pf/Pv rapid diagnostic test for malaria diagnosis in the Western Brazilian Amazon.
作者信息
Costa Monica Regina Farias, Barcelos Ana Luísa Rubert, Camargo Maria Angélica de, Melo Gisely Cardoso de, Almeida Anne Cristine, Costa Allyson Guimarães da, Sousa Jose Diego de Brito, Melo Marly Marques de, Alecrim Maria das Graças Costa, Lacerda Marcus Vinicius Guimarães de, Monteiro Wuelton Marcelo
机构信息
Instituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Pesquisa e Desenvolvimento, Wama Diagnóstica, São Carlos, SP, Brasil.
出版信息
Rev Soc Bras Med Trop. 2019 Jan 17;52:e20170450. doi: 10.1590/0037-8682-0450-2017.
INTRODUCTION
Rapid diagnostic tests (RDTs) for detecting Plasmodium antigens have become increasingly common worldwide. We aimed to evaluate the accuracy of the Immuno-Rapid Malaria Pf/Pv RDT in detecting Plasmodium vivax infection compared to standard thick blood smear (TBS) under microscopy.
METHODS
Hundred and eighty-one febrile patients from the hospital's regular admissions were assessed using TBS and RDT in a blinded experiment.
RESULTS
RDT showed a sensitivity of 98.9%, specificity of 100%, and accuracy of 99.5% for P. vivax infection when compared to TBS.
CONCLUSIONS
The RDT is highly accurate, making it a valuable diagnostic tool for P. vivax infection.
引言
用于检测疟原虫抗原的快速诊断检测（RDT）在全球范围内已变得越来越普遍。我们旨在评估免疫快速疟疾Pf/Pv RDT与显微镜下标准厚血涂片（TBS）相比检测间日疟原虫感染的准确性。
方法
在一项盲法实验中，对医院常规住院的181名发热患者使用TBS和RDT进行评估。
结果
与TBS相比，RDT检测间日疟原虫感染的灵敏度为98.9%，特异性为100%，准确性为99.5%。
结论
RDT具有高度准确性，使其成为间日疟原虫感染的一种有价值的诊断工具。
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