Nilles M, Alles J U, Paul E
Funktionsbereich Dermatologische Mikromorphologie, Klinikum der Justus-Liebig-Universität Giessen.
Hautarzt. 1988 Aug;39(8):531-3.
Cutaneous angiosarcoma are rare tumours and occur particularly rarely on the extremities. There are only a few reports in the literature concerning their clinical and catamnestic behaviour. We report the case of a 57-year-old male North African with a large exophytic and nodular tumour of the left forearm that showed a vasoformative histological pattern. The endothelial cell origin was proven by immunocytochemistry using endothelial cell antibodies such as anti-vWf (syn.:anti F VIII R:Ag), UEA I and the monoclonal antibody BMA 120. The patient's history revealed that the neoplasm had grown slowly for more than 15 years. After partial resection, the tumour enlarged rapidly and the patient died of widespread metastases.
皮肤血管肉瘤是罕见肿瘤，尤其极少发生于四肢。文献中仅有少数关于其临床及随访行为的报道。我们报告一例57岁北非男性病例，其左前臂有一个巨大的外生性结节状肿瘤，组织学表现为血管形成模式。通过使用内皮细胞抗体如抗血管性血友病因子（同义词：抗F VIII R:Ag）、荆豆凝集素I和单克隆抗体BMA 120进行免疫细胞化学检测，证实了内皮细胞起源。患者病史显示该肿瘤已缓慢生长超过15年。部分切除后，肿瘤迅速增大，患者死于广泛转移。
