Kwon Chan-Young, Yoon Sang-Hoon, Lee Boram, Leem Jungtae
Chung-Yeon Central Institute, Gwangju, Republic of Korea.
Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Medicine (Baltimore). 2019 Jan;98(3):e14160. doi: 10.1097/MD.0000000000014160.
This systematic review protocol describes the methods that will be used to evaluate the efficacy and safety of acupotomy for the treatment of lumbar spinal stenosis.
The following electronic databases will be searched until December 2018 without language or publication status restrictions: five English databases, that is Medline, the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Allied and Complementary Medicine Database (AMED), and Cumulative Index to Nursing and Allied Health Literature (CINAHL); three Korean databases, that is Oriental Medicine Advanced Searching Integrated System (OASIS), Research Information Service System (RISS), and Korea Citation Index (KCI); and three Chinese databases, that is China National Knowledge Infrastructure (CNKI), Wanfang Data, and VIP. Any clinical, randomized controlled trials using acupotomy for lumbar spinal stenosis treatment will be included. Changes in the degrees of pain and function will be assessed as primary outcomes. The total effective rate, changes in quality of life, adverse events, and amount of rescue medication used will be evaluated as secondary outcomes. Two independent researchers will perform study selection, data extraction, and risk of bias assessment. If applicable, a meta-analysis will be performed using RevMan version 5.3, with the results expressed as risk ratios or mean differences with 95% confidence intervals. According to a heterogeneity test or the number of studies included, fixed effects or random effects model will be used. The risk of bias tool from the Cochrane group will be used to evaluate the methodological quality of the included studies.
Ethical approval is not required because individual patient data will not be included in this study. The findings of this systematic review will be disseminated through a peer-reviewed publication or conference presentations.
CRD42018116567.
本系统评价方案描述了用于评估针刀治疗腰椎管狭窄症的疗效和安全性的方法。
将检索以下电子数据库至2018年12月，不受语言或出版状态限制：五个英文数据库，即医学索引数据库（Medline）、考克兰系统评价数据库（CENTRAL）、荷兰医学文摘数据库（EMBASE）、补充与替代医学数据库（AMED）和护理学与健康照护领域累积索引数据库（CINAHL）；三个韩文数据库，即韩医高级检索集成系统（OASIS）、研究信息服务系统（RISS）和韩国引文索引数据库（KCI）；以及三个中文数据库，即中国知网（CNKI）、万方数据和维普资讯。将纳入任何使用针刀治疗腰椎管狭窄症的临床随机对照试验。疼痛程度和功能的变化将作为主要结局进行评估。总有效率、生活质量变化、不良事件和使用的急救药物量将作为次要结局进行评估。两名独立研究人员将进行研究选择、数据提取和偏倚风险评估。如果适用，将使用RevMan 5.3版进行荟萃分析，结果以风险比或平均差及95%置信区间表示。根据异质性检验或纳入研究的数量，将使用固定效应或随机效应模型。将使用考克兰小组的偏倚风险工具来评估纳入研究的方法学质量。
由于本研究不纳入个体患者数据，因此无需伦理批准。本系统评价的结果将通过同行评审出版物或会议报告进行传播。
国际前瞻性系统评价注册库（PROSPERO）注册号：CRD42018116567。
