a School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University , Wenzhou , Zhejiang , China.
b Key Laboratory of Vision Science , Ministry of Health P.R. China , Wenzhou , Zhejiang , China.
Curr Eye Res. 2019 Jun;44(6):607-613. doi: 10.1080/02713683.2019.1570275. Epub 2019 Jan 30.
To study the capsule morphology in pseudophakic eyes on the three-dimensional level using high-speed swept-source optical coherence tomography (SSOCT).
This study collected patients with age-related cataract and divided them into two groups according to the anterior capsule and intraocular lens (IOL) optic relationship: total anterior capsule overlap (360°, Group-T) and partial anterior capsule overlap (<360°, Group-P). One standard SSOCT radial scanning was performed in all eyes at 1 day, 1 week, 1 month, and 3 months postoperatively.
Thirty-two eyes from 25 patients were enrolled in the Group-T and 17 eyes from 13 patients in the Group-P. No eyes achieved complete adhesion between IOL optic and posterior capsule at 1 day after the surgery. However, the rate of complete adhesion was low (15/49, 30.6%) even at 3 months postoperatively and there was no statistically difference between Group-T and Group-P (21.9% vs. 47.1%, > 0.05). At 1 day, 1 week, 1 month, and 3 months after the surgery, the capsule bend index (CBI) in the Group-T was 0.02 ± 0.09, 1.35 ± 1.48, 3.60 ± 0.54, and 3.88 ± 0.19, respectively. CBI rises linearly during the first month and the rise goes stable relatively with the great reduction of standard deviation in the following 2 months (All < 0.05). The anterior capsule opening area and diameter were both reduced in the first month, and then they both became stable.
With square-edge IOL, posterior capsule opacification risk is still high in most eyes at 3 months postoperatively for the complete adhesion of posterior capsule and IOL was only achieved in 30.6% eyes. IOL-in-bag may be driven by the significant capsule bag changes especially in the first month postoperatively.
使用高速扫频光学相干断层扫描（SSOCT）在三维水平上研究人工晶状体眼的囊袋形态。
本研究收集了年龄相关性白内障患者，并根据前囊和人工晶状体（IOL）光学关系将其分为两组：完全前囊重叠（360°，Group-T）和部分前囊重叠（<360°，Group-P）。所有患者术后第 1、1 周、1 个月和 3 个月分别进行 1 次标准 SSOCT 径向扫描。
共纳入 25 例患者的 32 只眼（Group-T）和 13 例患者的 17 只眼（Group-P）。术后第 1 天，没有一只眼的 IOL 光学面与后囊完全粘连，但即使在术后 3 个月，完全粘连的比例也很低（15/49，30.6%），且两组之间无统计学差异（21.9%比 47.1%，>0.05）。术后第 1、1 周、1 个月和 3 个月，Group-T 的囊袋弯曲指数（CBI）分别为 0.02±0.09、1.35±1.48、3.60±0.54 和 3.88±0.19。术后第 1 个月，CBI 呈线性上升，随后 2 个月，CBI 上升趋于稳定，标准差明显减小（均<0.05）。术后第 1 个月，前囊开口面积和直径均减小，随后趋于稳定。
对于术后 3 个月的大多数患者，由于后囊和 IOL 完全粘连的比例仅为 30.6%，仍存在较高的后囊混浊风险。IOL 囊袋内可能受到囊袋显著变化的驱动，特别是在术后第 1 个月。
