Lücking C H, Struppler A
MMW Munch Med Wochenschr. 1978 May 12;120(19):657-60.
Facial neuralgia appears in a variety of forms which have different fundamental pathophysiological mechanisms. Of decisive importance are neuralgias with sensitive trigeminal, intermediate (sensory root), glossopharyngeal and vagus nerves which are caused by functional disturbances or damage to the nerve. In addition, projected or referred pain occurs in intracranial and cervical affections. A vascular origin may be assumed for Horton's neuralgia. This periodic paroxysmal and unilateral facial neuralgia is related to migraine. Serotonin, histamine and plasma kinin may be important eliciting factors; the concomitant symptoms of lachyrmation and rhinorrhea, reddening of the eyes and the face and a transitory Horner's syndrome suggest participation of the sympathetic and parasympathetic systems. Consideration of the previously known pathophysiological mechanisms permits a differentiated therapy for the various facial neuralgias.
面部神经痛有多种形式，其基本病理生理机制各不相同。具有决定性意义的是由三叉神经、中间神经（感觉根）、舌咽神经和迷走神经的功能性紊乱或损伤引起的神经痛。此外，颅内和颈部病变会出现投射性或牵涉性疼痛。霍顿神经痛可能源于血管。这种周期性发作的单侧面部神经痛与偏头痛有关。血清素、组胺和血浆激肽可能是重要的诱发因素；伴随的流泪、流涕、眼睛和面部发红以及短暂性霍纳综合征等症状表明交感神经和副交感神经系统参与其中。考虑到先前已知的病理生理机制，可为各种面部神经痛提供差异化治疗。
