Mujtaba Bilal, Nassar Sameh M, Aslam Rizwan, Garg Naveen, Madewell John E, Taher Ahmed, Hanafy Abdelrahman K, Whitman Gary
Department of Diagnostic Imaging, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Department of Diagnostic Imaging, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Curr Probl Diagn Radiol. 2020 Mar-Apr;49(2):116-123. doi: 10.1067/j.cpradiol.2019.01.001. Epub 2019 Jan 3.
Extraskeletal osteosarcoma are rare malignant mesenchymal neoplasms of soft tissues representing around 1% of all soft tissue. The exact mechanism of tumorigenesis of primary breast osteosarcoma is still unclear. However, most of the cases develop without a recognized etiologic factor. Primary osteosarcoma of the breast is often initially misdiagnosed as breast fibroadenoma. Different imaging modalities and pathology play important role in differentiating breast osteosarcoma from other benign and malignant lesions of the breast resulting in dramatic change in the management.
骨外骨肉瘤是罕见的软组织恶性间叶性肿瘤，约占所有软组织肿瘤的1%。原发性乳腺骨肉瘤的确切肿瘤发生机制仍不清楚。然而，大多数病例在没有公认病因的情况下发生。乳腺原发性骨肉瘤最初常被误诊为乳腺纤维腺瘤。不同的影像学检查方法和病理学检查在鉴别乳腺骨肉瘤与乳腺其他良恶性病变方面发挥着重要作用，从而导致治疗方案的巨大改变。
