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一名15个月大男孩的巨大胸腺增生:病例报告及文献综述

Massive thymic hyperplasia in a 15-month-old boy: Case report and literature review.

作者信息

Tadiotto Elisa, Clemente Maria, Pecoraro Luca, Piacentini Giorgio, Degani Daniela, Pietrobelli Angelo

机构信息

Paediatric Clinic, Department of Life and Reproduction Sciences Azienda Ospedaliera Universitaria Integrata Verona Italy.

Pennington Biomedical Research Center Baton Rouge Louisiana.

出版信息

Clin Case Rep. 2018 Nov 10;7(1):27-31. doi: 10.1002/ccr3.1896. eCollection 2019 Jan.

DOI:10.1002/ccr3.1896
PMID:30656002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6333069/
Abstract

A surgical approach is the choice in young infants with MTH, who are furthest from the time of physiological involution of the thymus, and when the thymus achieves the largest relative size, a surgical approach is the choice. Steroid therapy has been shown to be ineffective (4, 9, 16, 18-20). No surgical complications have been reported, and the outcome is excellent. Recurrence has been seen in only one case.

摘要

对于患有MTH的小婴儿来说,手术治疗是一种选择,因为他们距离胸腺生理性退化的时间最远,而且当胸腺达到最大相对大小时,手术治疗是首选。已证明类固醇疗法无效(4, 9, 16, 18 - 20)。未报告手术并发症,且预后良好。仅1例出现复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f014/6333069/9d106e97d9ac/CCR3-7-27-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f014/6333069/e26d547ebb1f/CCR3-7-27-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f014/6333069/9d106e97d9ac/CCR3-7-27-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f014/6333069/e26d547ebb1f/CCR3-7-27-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f014/6333069/9d106e97d9ac/CCR3-7-27-g002.jpg

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本文引用的文献

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Case Rep Radiol. 2018 May 10;2018:7305619. doi: 10.1155/2018/7305619. eCollection 2018.
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Aplastic Anemia as an Immune-mediated Complication of Thymoma: A Case Report.
J Pediatr Hematol Oncol. 2018 Oct;40(7):e464-e466. doi: 10.1097/MPH.0000000000001140.
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Expression of receptor for advanced glycation end-products (RAGE) in thymus from myasthenia patients.重症肌无力患者胸腺中晚期糖基化终末产物受体(RAGE)的表达
Front Oncol. 2023 Jan 6;12:1077777. doi: 10.3389/fonc.2022.1077777. eCollection 2022.
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True thymic hyperplasia causing pure red cell aplasia: a case report.真性胸腺增生致纯红细胞再生障碍:病例报告。
Interact Cardiovasc Thorac Surg. 2022 Mar 31;34(4):697-699. doi: 10.1093/icvts/ivab301.
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[True thymic hyperplasia : Differential diagnosis of thymic mass lesions in neonates and children].[真性胸腺增生:新生儿及儿童胸腺肿块病变的鉴别诊断]
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