一名青年成年患者的胸腺瘤相关性重症肌无力，胸腺切除术后并发副肿瘤性边缘叶脑炎和系统性红斑狼疮：病例报告

Liu Robin, Dar A Rashid, Tay Keng Yeow, Nicolle Mike W, Inculet Richard I

Internal Medicine, Western University, London, CAN.

Oncology, Schulich School of Medicine & Dentistry, Western University, London, CAN.

Cureus. 2018 Nov 13;10(11):e3581. doi: 10.7759/cureus.3581.

We report a young adult with thymoma-associated myasthenia gravis (MG) who, following thymectomy, developed paraneoplastic limbic encephalitis (LE) and systemic lupus erythematosus (SLE). Although thymomas commonly co-occur with MG, LE is an uncommon autoimmune sequela. Herein, we discuss the pathophysiology of paraneoplastic LE and its management. Our report also highlights an unusual case of a thymoma patient who presented with multiple autoimmune disorders. The treatment of such a patient is therefore challenging and requires care from multiple specialized teams.

我们报告了一名患有胸腺瘤相关重症肌无力（MG）的年轻成人，该患者在胸腺切除术后发生了副肿瘤性边缘叶脑炎（LE）和系统性红斑狼疮（SLE）。虽然胸腺瘤常与MG同时出现，但LE是一种罕见的自身免疫性后遗症。在此，我们讨论副肿瘤性LE的病理生理学及其管理。我们的报告还突出了一名出现多种自身免疫性疾病的胸腺瘤患者的罕见病例。因此，对此类患者的治疗具有挑战性，需要多个专业团队的护理。