Department of Internal Medicine, Hadassah-Hebrew University Medical Center, Israel.
J Neurol Sci. 2012 Jun 15;317(1-2):146-7. doi: 10.1016/j.jns.2012.03.007. Epub 2012 Apr 6.
Thymoma is associated with multiple autoimmune disorders, most commonly myasthenia gravis (MG). However, symptomatic MG may first present following thymectomy. We report an unusual patient with paraneoplastic limbic encephalitis diagnosed a few months after total thymectomy for asymptomatic thymoma, followed 18 years later by the onset of symptomatic MG without evidence of tumor recurrence.
胸腺瘤与多种自身免疫性疾病相关,最常见的是重症肌无力(MG)。然而,有症状的 MG 可能在胸腺切除术后首次出现。我们报告了一例不常见的患者,在无症状胸腺瘤行全胸腺切除术几个月后被诊断为副肿瘤性边缘叶脑炎,18 年后出现有症状的 MG,且无肿瘤复发的证据。