International Joint Research Laboratory for Biointerface and Biodetection, State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
Adv Mater. 2020 Oct;32(41):e1802075. doi: 10.1002/adma.201802075. Epub 2019 Jan 17.
The development of artificial chiral architectures, especially chiral inorganic nanostructures, has greatly promoted research into chirality in nanoscience. The nanoscale chirality of artificial chiral nanostructures offers many new application opportunities, including chiral catalysis, asymmetric synthesis, chiral biosensing, and others that may not be allowed by natural chiral molecules. Herein, the progress achieved during the past decade in chirality-associated biological applications (biosensing, biolabeling, and bioimaging) combined with individual chiral nanostructures (such as chiral semiconductor nanoparticles and chiral metal nanoparticles) or chiral assemblies is discussed.
人工手性结构的发展，特别是手性无机纳米结构的发展，极大地推动了纳米科学中手性的研究。人工手性纳米结构的纳米级手性为手性催化、不对称合成、手性生物传感等提供了许多新的应用机会，这些应用机会是天然手性分子所不允许的。本文讨论了过去十年中与手性相关的生物应用（生物传感、生物标记和生物成像）方面的进展，同时还讨论了单个手性纳米结构（如手性半导体纳米粒子和手性金属纳米粒子）或手性组装体。
