Artificial Chiral Probes and Bioapplications.

The development of artificial chiral architectures, especially chiral inorganic nanostructures, has greatly promoted research into chirality in nanoscience. The nanoscale chirality of artificial chiral nanostructures offers many new application opportunities, including chiral catalysis, asymmetric synthesis, chiral biosensing, and others that may not be allowed by natural chiral molecules. Herein, the progress achieved during the past decade in chirality-associated biological applications (biosensing, biolabeling, and bioimaging) combined with individual chiral nanostructures (such as chiral semiconductor nanoparticles and chiral metal nanoparticles) or chiral assemblies is discussed.