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基孔肯雅病毒的垂直传播:一个全球性的关注点。

Vertical transmission of chikungunya virus: a worldwide concern.

机构信息

Hospital Maternidade Sofia Feldman, Minas Gerais, MG, Brazil.

Hospital Maternidade Sofia Feldman, Minas Gerais, MG, Brazil; Hospital Infantil João Paulo II, FHEMIG, Minas Gerais, MG, Brazil.

出版信息

Braz J Infect Dis. 2024 May-Jun;28(3):103747. doi: 10.1016/j.bjid.2024.103747. Epub 2024 May 6.

Abstract

The Chikungunya Virus (CHIKV) already has endemic circulation in about 100 countries and the number of infected patients increases every year, due to the effectiveness of the vector and human universal susceptibility to infection. The virus can also be transmitted from mother to child, more frequently intrapartum. About 50 % of neonates with CHIKV symptoms will have neurodevelopmental delay. It is therefore an infection of worldwide concern with a great impact on people's quality of life. The objective of this work is to describe two cases of confirmed vertical transmission by chikungunya virus, one of them with intrauterine infection and death of the neonate. Neonates with vertical chikungunya infection may present with clinical sepsis in the first few days of life, which is why this is a very important diagnosis, especially during outbreaks of the infection.

摘要

基孔肯雅热病毒(CHIKV)已经在大约 100 个国家流行,由于媒介的有效性和人类普遍易感性,每年感染患者的数量都在增加。该病毒也可以通过母婴传播,更常见于分娩期间。约有 50%有 CHIKV 症状的新生儿会出现神经发育迟缓。因此,这是一种全球性关注的感染,对人们的生活质量有很大影响。这项工作的目的是描述两例经确证的垂直传播基孔肯雅热病毒感染病例,其中一例为宫内感染且新生儿死亡。垂直感染基孔肯雅热病毒的新生儿可能在生命的头几天出现临床败血症,因此这是一个非常重要的诊断,特别是在感染爆发期间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9057/11169065/78b155df903c/gr1.jpg

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