Larbre J P, Nicolas J F, Larbre B, Perret-Liaudet P, Adam C, Thivolet J
Clinique dermatologique, hôpital E. Herriot, Lyon.
Rev Med Interne. 1988 Sep-Oct;9(4):429-34. doi: 10.1016/s0248-8663(88)80148-6.
The authors review the drug treatment of Raynaud's disease. Many substances have been used including nitrate derivatives, calcium antagonists, alpha blockers, angiotensin converting enzyme inhibitors, prostaglandin E1, E2 and I2, and ketanserin. The efficacy of these drugs is often partial and variable. The indications are discussed with respect to the clinical course and etiology of the Raynaud's phenomenon.
作者们综述了雷诺病的药物治疗。已使用过多种物质,包括硝酸酯衍生物、钙拮抗剂、α受体阻滞剂、血管紧张素转换酶抑制剂、前列腺素E1、E2和I2以及酮色林。这些药物的疗效往往是部分的且存在差异。针对雷诺现象的临床病程和病因对用药指征进行了讨论。