Kikano Elias, Grosse Hokamp Nils, Ciancibello Leslie, Ramaiya Nikhil, Kosmas Christos, Gupta Amit
Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Institute for Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany.
3D Print Med. 2019 Jan 18;5(1):1. doi: 10.1186/s41205-019-0038-y.
One of the key steps in generating three-dimensional (3D) printed models in medicine is segmentation of radiologic imaging. The software tools used for segmentation may be automated, semi-automated, or manual which rely on differences in material density, attenuation characteristics, and/or advanced software algorithms. Spectral Detector Computed Tomography (SDCT) is a form of dual energy computed tomography that works at the detector level to generate virtual monoenergetic images (VMI) at different energies/ kilo-electron volts (keV). These VMI have varying contrast and attenuation characteristics relative to material density. The purpose of this pilot project is to explore the use of VMI in segmentation for medical 3D printing in four separate clinical scenarios. Cases were retrospectively selected based on varying complexity, value of spectral data, and across multiple clinical disciplines (Vascular, Cardiology, Oncology, and Orthopedic).
In all four clinical cases presented, the segmentation process was qualitatively reported as easier, faster, and increased the operator's confidence in obtaining accurate anatomy. All cases demonstrated a significant difference in the calculated Hounsfield Units between conventional and VMI data at the level of targeted segmentation anatomy. Two cases would not have been feasible for segmentation and 3D printing using conventional images only. VMI data significantly reduced conventional CT artifacts in one of the cases.
Utilization of VMI from SDCT can improve and assist the segmentation of target anatomy for medical 3D printing by enhancing material contrast and decreasing CT artifact.
医学三维(3D)打印模型生成的关键步骤之一是放射影像的分割。用于分割的软件工具可以是自动化、半自动或手动的,这些工具依赖于材料密度、衰减特性和/或先进的软件算法的差异。光谱探测器计算机断层扫描(SDCT)是一种双能计算机断层扫描形式,它在探测器层面工作,以生成不同能量/千电子伏特(keV)的虚拟单能图像(VMI)。这些VMI相对于材料密度具有不同的对比度和衰减特性。本试点项目的目的是在四个不同的临床场景中探索VMI在医学3D打印分割中的应用。根据不同的复杂性、光谱数据价值以及多个临床学科(血管、心脏、肿瘤和骨科)回顾性选择病例。
在所有四个呈现的临床病例中,定性报告显示分割过程更轻松、更快,并且增强了操作员获取准确解剖结构的信心。在目标分割解剖结构层面,所有病例在传统数据和VMI数据之间计算的亨氏单位均存在显著差异。仅使用传统图像进行分割和3D打印时,有两个病例是不可行的。在其中一个病例中,VMI数据显著减少了传统CT伪影。
利用SDCT的VMI可以通过增强材料对比度和减少CT伪影来改善和辅助医学3D打印中目标解剖结构的分割。