Costantini Manuela, Tuderti Gabriele, Minisola Francesco, Pompeo Vincenzo, Sentinelli Steno, Amoreo Carla A, Vallati Giulio, Poeta Maria L, Gallucci Michele, Simone Giuseppe
Department of Urology, IRCCS-Regina Elena National Cancer Institute, Rome, Italy; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Bari, Italy.
Department of Urology, IRCCS-Regina Elena National Cancer Institute, Rome, Italy.
Urology. 2019 May;127:13-18. doi: 10.1016/j.urology.2019.01.007. Epub 2019 Jan 16.
Splenic metastasis is uncommon and is usually associated with widespread disease. Isolated splenic metastases from renal cancer are also rarer and are often an incidental finding. This eventuality may turn into a dangerous scenario due to a spontaneous splenic rupture leading to sudden death. At the best of our knowledge, only few cases of metastasis from renal cell carcinoma (RCC) have been documented in the literature. We hereby present a literature review of these cases and report a case of isolated splenic metastasis in a young man on active follow-up for a clear cell RCC clear cell Renal Cell Carcinoma (ccRCC).
脾转移并不常见,通常与广泛播散性疾病相关。肾癌孤立性脾转移更为罕见,常为偶然发现。由于自发性脾破裂可导致猝死,这种情况可能会演变成危险的情形。据我们所知,文献中仅记载了少数肾细胞癌(RCC)转移的病例。我们在此对这些病例进行文献综述,并报告一例在对透明细胞肾细胞癌(ccRCC)进行积极随访的年轻男性患者中发生的孤立性脾转移病例。