Allergy department, Metz Regional Hospital, 1 allée du Château, 57530 Ars-Laquenexy, France.
Allergy department, Besançon University Hospital, 3 boulevard Flemming, 25030 Besançon, France.
Asian Pac J Allergy Immunol. 2020 Mar;38(1):29-30. doi: 10.12932/AP-010918-0399.
Fish roe is an extremely rare cause of anaphylaxis and although its consumption has increased in recent years. We described the case of a 59-year-old man, who experienced an anaphylactic reaction after consuming caviar. Skin prick-test were performed with Beluga caviar, salmon caviar, cod, salmon, hen egg yolk and egg white, ovalbumin, ovomucoid, shrimp and mold. Only SPT to Beluga caviar was positive. The absence of sensitization to fish and hen egg was confirmed by undetectable specific IgEs to cod, parvalbumin (Gad c 1 and Cyp c 1), egg yolk and egg white, ovalbumin and ovomucoid. An immunoblot was also performed and showed an IgE-reactive band indicated that the patient was sensitized to a 26 kDa protein in Beluga caviar. In the present case, immunoblotting of the patient's serum revealed a single IgE-reactive band at 26 kDa band, which does not appear to correspond to the previous cases.
鱼卵是引发过敏反应的极其罕见的原因，尽管近年来其食用量有所增加。我们描述了一位 59 岁男性的病例，他在食用鱼子酱后发生了过敏反应。对白鲸鱼子酱、三文鱼鱼子酱、鳕鱼、三文鱼、鸡蛋蛋黄和蛋清、卵白蛋白、卵转铁蛋白、虾和霉菌进行了皮肤点刺试验。只有白鲸鱼子酱的皮肤点刺试验呈阳性。通过未检测到鳕鱼、副肌球蛋白（ Gad c 1 和 Cyp c 1 ）、蛋黄和蛋清、卵白蛋白和卵转铁蛋白、卵白蛋白和卵转铁蛋白的特异性 IgE，证实了对鱼类和鸡蛋的无致敏性。还进行了免疫印迹，显示出 IgE 反应带，表明患者对白鲸鱼子酱中的 26 kDa 蛋白致敏。在本病例中，患者血清的免疫印迹显示在 26 kDa 带处有一条单独的 IgE 反应带，这似乎与以前的病例不同。
