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实验感染小鼠血清中弓形虫结构蛋白的证据。

Evidence of structural proteins of Toxoplasma gondii in sera of experimentally infected mice.

作者信息

Hassl A, Aspöck H, Flamm H

机构信息

Abteilung für Medizinische Parasitologie, Hygiene-Instituts der Universität Wien.

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A. 1988 Nov;270(1-2):310-2. doi: 10.1016/s0176-6724(88)80168-8.

DOI:10.1016/s0176-6724(88)80168-8
PMID:3066076
Abstract

The present study was performed to clarify whether structural proteins are constituants of the antigens of Toxoplasma gondii which circulate in the sera of experimentally infected mice. Rabbits were immunized with mice sera containing circulating antigen, the rabbit sera were then tested for antibodies against Toxoplasma gondii. Low titers of specific antibodies, directed against cell wall proteins, could be detected. Thus, the circulating antigen must at least partially consist of structural proteins.

摘要

本研究旨在阐明在实验感染小鼠血清中循环的弓形虫抗原的组成成分是否包含结构蛋白。用含有循环抗原的小鼠血清免疫兔子,然后检测兔血清中抗弓形虫的抗体。可以检测到针对细胞壁蛋白的低滴度特异性抗体。因此,循环抗原至少部分由结构蛋白组成。

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