Olasode B J, Shokunbi M T, Aghadiuno P U
Department of Pathology, University College Hospital, Ibadan, Nigeria.
East Afr Med J. 2000 Jan;77(1):4-8.
To determine the pattern of histopathological variants of intracranial neoplasms, relative distribution of the variants in the age groups and also to determine the gender differences that exist in these tumours.
Case control study.
Department of Pathology, University College Hospital, Ibadan, Nigeria.
Two hundred and ten histologically confirmed cases of intracranial neoplasms seen during eleven-year period (1980 to 1990) were analysed.
Slides of tumours stained with haematoxylin and eosin, reticulin and phosphotungstic acid haematoxylin.
Two hundred and ten intracronial neoplasms comprising 172 primary and 48 secondary neoplasms were seen. One hundred and thirty five neoplasms occurred in adults and 75 in children. There was no gender difference, the ratio being 1:1. Gliomas accounted for the largest group of tumours followed by metastases to the brain. Of the gliomas, astrocytoma was the commonest. Craniopharyngiomas were found to be common in children. Germ cell tumours were found to be uncommon.
Gliomas are the commonest group of intracranial neoplasms in both adults and children. This is followed by metastatic tumours. Tumours of the sella turcica are predominantly found in children. Involvement of the brain in disseminated Burkitt's lymphomas is predominantly found in Africans as the Burkitt's tumour is uncommon in non Africans.
确定颅内肿瘤组织病理学变异的模式、各变异在不同年龄组中的相对分布，并确定这些肿瘤中存在的性别差异。
病例对照研究。
尼日利亚伊巴丹大学学院医院病理科。
对11年期间（1980年至1990年）所见的210例经组织学确诊的颅内肿瘤病例进行分析。
肿瘤切片用苏木精和伊红、网状纤维和磷钨酸苏木精染色。
共观察到210例颅内肿瘤，其中原发性肿瘤172例，继发性肿瘤48例。135例肿瘤发生于成人，75例发生于儿童。无性别差异，比例为1:1。胶质瘤是最大的肿瘤组，其次是脑转移瘤。在胶质瘤中，星形细胞瘤最为常见。颅咽管瘤在儿童中较为常见。生殖细胞肿瘤不常见。
胶质瘤是成人和儿童中最常见的颅内肿瘤组。其次是转移性肿瘤。蝶鞍区肿瘤主要见于儿童。非洲人散发性伯基特淋巴瘤累及脑部的情况较为常见，因为伯基特肿瘤在非非洲人中不常见。
