Gordon Stephen B, Chinula Lameck, Chilima Ben, Mwapasa Victor, Dadabhai Sufia, Mlombe Yohannie
Malawi LIverpool Wellcome Trust Clinical Research Program, Blantyre, Malawi.
University of North Carolina Research, University of North Carolina, Blantyre, Malawi.
Wellcome Open Res. 2018 Dec 19;3:141. doi: 10.12688/wellcomeopenres.14668.2. eCollection 2018.
Research participant remuneration has been variable and inconsistent world-wide for many years owing to uncertainty regarding best practice and a lack of written guidelines for investigators and research ethics committees. Recent recommendations are that researchers and regulators should develop regionally appropriate written guidelines to define reasonable remuneration based on expense reimbursement, compensation for time and burden associated with participation. Incentives to motivate participation are acceptable in specific circumstances. We wished to develop regionally informed, precise and applicable guidelines in Malawi that might also be generally useful for African researchers and review committees. We therefore reviewed the current literature and developed widely applicable and specific remuneration tables using acceptable and evidence-based payment rationales. There were good international guidelines and limited published regional guidelines. There were published examples of best practice and sufficient material to suggest a structured remuneration table. The rationale and method for the table were discussed at an inter-disciplinary workshop resulting in a reimbursement and compensation model with fixed rates. Payment is recommended pro rata and equally across a study. Transparent, fair remuneration of research participants is recommended by researchers and regulators in Malawi. The means to achieve this are now presented in the Malawi research participant remuneration table.
多年来，由于最佳实践存在不确定性，且缺乏针对研究者和研究伦理委员会的书面指南，研究参与者的报酬在全球范围内一直存在差异且不一致。最近的建议是，研究人员和监管机构应制定适合当地情况的书面指南，根据费用报销、对参与研究的时间和负担的补偿来界定合理报酬。在特定情况下，鼓励参与的激励措施是可以接受的。我们希望在马拉维制定具有地区针对性、精确且适用的指南，这些指南可能对非洲研究人员和审查委员会也普遍有用。因此，我们查阅了当前的文献，并使用可接受的、基于证据的支付理由制定了广泛适用的具体报酬表。国际上有很好的指南，但已发表的地区性指南有限。有已发表的最佳实践示例以及足够的材料来建议制定一个结构化的报酬表。该报酬表的理由和方法在一个跨学科研讨会上进行了讨论，得出了一个固定费率的报销和补偿模式。建议按比例并在整个研究中平等支付。马拉维的研究人员和监管机构建议对研究参与者进行透明、公平的报酬支付。实现这一目标的方法现在呈现在马拉维研究参与者报酬表中。
