Baber R J, McSweeney M B, Gill R W, Porter R N, Picker R H, Warren P S, Kossoff G, Saunders D M
Royal North Shore Hospital, Sydney, Australia.
Br J Obstet Gynaecol. 1988 Dec;95(12):1226-30. doi: 10.1111/j.1471-0528.1988.tb06810.x.
The waveforms of vessels supplying the ovaries of women on an in-vitro fertilization (IVF) programme were studied using transvaginal B-mode and Doppler ultrasound. There were 125 scans recorded in 65 women at weekly intervals from 3 days after embryo transfer or 5 days after gamete intrafallopian transfer (GIFT) until confirmation of pregnancy or onset of menses. At each examination the signals obtained from vessels supplying the ovaries were recorded and quantified using a resistance index (RI). Fifteen patients became pregnant of whom one has subsequently miscarried. There was a highly significant difference in the RI values between patients who became pregnant and those who did not; no patient who became pregnant had a RI greater than 0.5. Oestrogen to progesterone ratios were calculated in the subgroup of non-pregnant patients and there was no correlation between these values and the RI values. This new technique enables prediction of IVF treatment failure earlier than has been reported previously and may reflect the inadequacy of the corpus luteum.
利用经阴道B超和多普勒超声对接受体外受精（IVF）治疗方案的女性卵巢供血血管的波形进行了研究。在65名女性中记录了125次扫描，从胚胎移植后3天或配子输卵管内移植（GIFT）后5天开始，每周进行一次，直至确认怀孕或月经来潮。每次检查时，记录从卵巢供血血管获得的信号，并使用阻力指数（RI）进行量化。15名患者怀孕，其中1名随后流产。怀孕患者和未怀孕患者的RI值存在高度显著差异；怀孕的患者中没有RI大于0.5的。在未怀孕患者亚组中计算了雌激素与孕酮的比值，这些值与RI值之间没有相关性。这项新技术能够比之前报道的更早地预测IVF治疗失败，并且可能反映黄体功能不足。
