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将综合医院与专门的基于社区的酒精使用障碍治疗方法相结合的方法-一项实用型随机对照试验。

Making a bridge between general hospital and specialised community-based treatment for alcohol use disorder-A pragmatic randomised controlled trial.

机构信息

Unit of Clinical Alcohol Research, Clinical Institute, University of Southern Denmark, J.B. Winsløws Vej 20, Indgang 220B, 5000 Odense, Denmark; Psychiatric Department, University Function, Region of Southern Denmark, Denmark.

Unit of Clinical Alcohol Research, Clinical Institute, University of Southern Denmark, J.B. Winsløws Vej 20, Indgang 220B, 5000 Odense, Denmark; Psychiatric Department, University Function, Region of Southern Denmark, Denmark.

出版信息

Drug Alcohol Depend. 2019 Mar 1;196:51-56. doi: 10.1016/j.drugalcdep.2018.12.017. Epub 2019 Jan 17.

Abstract

AIM

To investigate if more patients in the intervention group attended specialized alcohol treatment compared with a treatment-as-usual group (TAU).

METHODS

Pragmatic randomized controlled trial where consecutive patients, admitted to somatic hospitals, filled out a lifestyle questionnaire with the Alcohol Use Disorder Identification Test (AUDIT) embedded. Patients scoring 8+ on AUDIT were included in the study. Included patients were randomized to either a Danish screening brief intervention and referral to treatment (SBIRT) called the Relay model or TAU depending on date of admission. The Relay group was offered a brief alcohol intervention by an outreach alcohol therapist. Patients scoring 16 points and above on the AUDIT test also received referral to alcohol treatment. Outcome was attendance at specialized outpatient alcohol treatment centres after discharge from hospital. Information on patients was gathered from municipal databases at 18 months follow-up.

RESULTS

A total of 3534 patients completed the questionnaire, and 609 patients (17%) scored AUDIT 8+. 48 patients were lost to follow-up, and the final sample had 561 patients. Only 33 patients (6%) attended outpatient treatment at 18-months follow-up, but significantly more patients in the Relay group sought alcohol treatment than in the TAU group (OR = 2.5 [1.2;5.2] (p = 0.017)). Number needed to treat (NNT) was 20 [95% CI 11.2;112.3].

CONCLUSION

The Relay intervention was associated with more patients attending specialized treatment, but further research is needed to establish if general hospitals are an excellent platform for performing SBIRT.

摘要

目的

调查干预组与常规治疗组(TAU)相比,是否有更多患者接受专门的酒精治疗。

方法

这是一项实用的随机对照试验,连续入院的患者填写了一份生活方式问卷,其中嵌入了酒精使用障碍识别测试(AUDIT)。AUDIT 得分 8 分及以上的患者被纳入研究。纳入的患者随机分为丹麦筛查简短干预和转介治疗(Relay 模型)或 TAU,具体取决于入院日期。Relay 组由一名外展酒精治疗师提供简短的酒精干预。AUDIT 测试得分 16 分及以上的患者也会被转介到酒精治疗。出院后患者在专门的门诊酒精治疗中心就诊的情况为结局。通过 18 个月的随访,从市数据库收集患者信息。

结果

共有 3534 名患者完成了问卷,609 名患者(17%)AUDIT 得分为 8 分及以上。48 名患者失访,最终样本为 561 名患者。只有 33 名患者(6%)在 18 个月随访时接受了门诊治疗,但 Relay 组寻求酒精治疗的患者明显多于 TAU 组(OR=2.5 [1.2;5.2](p=0.017))。需要治疗的人数(NNT)为 20 [95%CI 11.2;112.3]。

结论

Relay 干预与更多患者接受专门治疗相关,但需要进一步研究确定综合医院是否是执行 SBIRT 的理想平台。

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