奎宁过量：毒性与治疗综述

Quinine overdose: review of toxicity and treatment.

作者信息

Goldenberg A M, Wexler L F

机构信息

Department of Medicine, Boston City Hospital, Massachusetts.

出版信息

Clin Cardiol. 1988 Oct;11(10):716-8. doi: 10.1002/clc.4960111012.

DOI:10.1002/clc.4960111012

PMID:3066541

Abstract

Quinine sulfate is a commonly prescribed remedy for idiopathic nocturnal leg cramps and is now available "over the counter." A 24-year-old man ingested 8 g (a commonly dispensed quantity) of quinine sulfate in a suicide attempt. Despite hemoperfusion begun 10 h after ingestion, the patient died. This report reviews the toxic manifestations of quinine and the currently available modes of treatment.

摘要

硫酸奎宁是治疗特发性夜间腿部痉挛的常用处方药，现在可以“非处方”购买。一名24岁男子为自杀企图服用了8克（常用剂量）硫酸奎宁。尽管在摄入后10小时开始进行血液灌流，但患者仍死亡。本报告回顾了奎宁的毒性表现和目前可用的治疗方法。