Miller Iben Marie, Ahlehoff Ole, Vinding Gabrielle, Rytgaard Helene, Mogensen Ulla Brasch, Ring Hans Christian, Ellervik Christina, Jemec Gregor B E
Iben Marie Miller, MD, Department of Dermatology, Roskilde Hospital, Køgevej 7-13, 4000 Roskilde, Denmark;
Acta Dermatovenerol Croat. 2018 Dec;26(4):289-296.
Hidradenitis suppurativa (HS) is a chronic inflammatory dermatological disease with inflammatory mechanisms overlapping those of psoriasis, and both diseases have been associated with cardiovascular risk factors i.e. smoking and metabolic syndrome. Two studies have recently linked psoriasis with Atrial Fibrillation (AF). AF is the most frequently occurring cardiac arrhythmia in the general population and is typically accompanied by increased heart rate. Both AF and heart rate are linked with inflammation. The aim of the study was to investigate a potential association between HS and increased heart rate as well as AF. We performed a comparative cross-sectional study using digital measurements of heart rate and resting 12-lead electrocardiography (ECG) in combination with self-reported information when diagnosing AF. Our study comprised 32 individuals with HS from the hospital (the hospital HS group), 430 from the general population HS group (the population HS group), and 20,780 controls. Age and sex adjusted analysis demonstrated a significantly higher heart rate in the HS groups vs. controls (15% (range: 8-23%) higher for the hospital HS group and 4% (2-5%) higher for the population HS group). We found no association between HS and AF (P=0.1670).
化脓性汗腺炎（HS）是一种慢性炎症性皮肤病，其炎症机制与银屑病的炎症机制重叠，且这两种疾病都与心血管危险因素有关，即吸烟和代谢综合征。最近有两项研究将银屑病与心房颤动（AF）联系起来。AF是普通人群中最常见的心律失常，通常伴有心率加快。AF和心率都与炎症有关。本研究的目的是调查HS与心率加快以及AF之间的潜在关联。我们进行了一项比较横断面研究，在诊断AF时，结合自我报告信息，使用心率数字测量和静息12导联心电图（ECG）。我们的研究包括32名来自医院的HS患者（医院HS组）、430名来自普通人群的HS患者（人群HS组）和20780名对照。年龄和性别调整分析显示，HS组的心率显著高于对照组（医院HS组高15%（范围：8 - 23%），人群HS组高4%（2 - 5%））。我们发现HS与AF之间没有关联（P = 0.1670）。
