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经尿道前列腺切除术前列腺切除重量对术后性功能障碍影响的研究:一项基于人群的研究。

Investigation of prostate resected weight on postoperative sexual dysfunction following transurethral resection of prostate surgery: a population-based study.

作者信息

Liu Fu-Chao, Shen Shih-Jyun, Lin Jr-Rung, Yu Huang-Ping

机构信息

Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan,

College of Medicine, Chang Gung University, Taoyuan, Taiwan,

出版信息

Ther Clin Risk Manag. 2019 Jan 10;15:113-118. doi: 10.2147/TCRM.S186822. eCollection 2019.

DOI:10.2147/TCRM.S186822
PMID:30666121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6330969/
Abstract

BACKGROUND

Benign prostate hyperplasia, a common disease in elderly men, can be surgically treated with transurethral resection of the prostate (TURP). Postoperative sexual dysfunction is a major issue and is influenced by many factors. The present study aimed to assess whether the intraoperative resected prostate weight influences the probability of postoperative sexual dysfunction.

METHODS

This population-based study included 41,574 patients from the Nation Health Insurance Research Database who had undergone TURP once between 1997 and 2013. All patients were divided into three groups according to the resected prostate weight (low, medium, and high groups). Perioperative risk factors influencing sexual function were analyzed. The chi-squared test and Fisher's exact test were used to analyze differences in demographic data. The Cox proportional hazard regression analysis was used to analyze the HRs. All statistical analyses were two-sided, and a -value <0.05 was considered statistically significant.

RESULTS

Of the 41,574 patients, 1,168 had postoperative sexual dysfunction after surgery. The incidence was not significantly different among the three resected prostate weight groups. Younger patients and patients with histories of chronic renal disease, ischemic heart disease, and obesity had higher prevalence of postoperative sexual dysfunction. Additionally, the onset time of sexual dysfunction was not significantly different among the three resected prostate weight groups.

CONCLUSION

Among patients undergoing TURP in Taiwan, the resected prostate weight does not seem to be related to the presence or onset time of postoperative sexual dysfunction.

摘要

背景

良性前列腺增生是老年男性的常见疾病,可通过经尿道前列腺切除术(TURP)进行手术治疗。术后性功能障碍是一个主要问题,受多种因素影响。本研究旨在评估术中切除的前列腺重量是否会影响术后性功能障碍的发生概率。

方法

这项基于人群的研究纳入了41574例来自国民健康保险研究数据库的患者,这些患者在1997年至2013年间接受过一次TURP手术。所有患者根据切除的前列腺重量分为三组(低、中、高组)。分析了影响性功能的围手术期危险因素。采用卡方检验和Fisher精确检验分析人口统计学数据的差异。采用Cox比例风险回归分析来分析风险比(HRs)。所有统计分析均为双侧检验,P值<0.05被认为具有统计学意义。

结果

在41574例患者中,1168例术后出现性功能障碍。三组切除前列腺重量组之间的发生率无显著差异。年轻患者以及有慢性肾病、缺血性心脏病和肥胖病史的患者术后性功能障碍的患病率较高。此外,三组切除前列腺重量组之间性功能障碍的发病时间无显著差异。

结论

在台湾接受TURP手术的患者中,切除的前列腺重量似乎与术后性功能障碍的存在或发病时间无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de2/6330969/499413b773f3/tcrm-15-113Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de2/6330969/60d709c1b3f5/tcrm-15-113Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de2/6330969/499413b773f3/tcrm-15-113Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de2/6330969/60d709c1b3f5/tcrm-15-113Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8de2/6330969/499413b773f3/tcrm-15-113Fig2.jpg

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