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基于性别和种族的人乳头瘤病毒(HPV)感染风险因素的理解。

Understanding of risk factors for the human papillomavirus (HPV) infection based on gender and race.

机构信息

Saint Louis University Cancer Center, 3655 Vista Avenue, 3rd Floor West Pavilion, St. Louis, MO, 63110, USA.

Saint Louis University School of Medicine, Department of Otolaryngology-Head and Neck Surgery, St. Louis, MO, 63110, USA.

出版信息

Sci Rep. 2019 Jan 22;9(1):297. doi: 10.1038/s41598-018-36638-z.

Abstract

This study assessed if race and gender predict known sexual risk factors associated with HPV. Data (n = 301) were from a cross-sectional study conducted at a drag racing event on September 12-13, 2015 in Madison, Illinois. Both multivariable logistic and linear regression models estimated the association between race, gender, and sexual risk factors. About 63% of participants were males, and 65% identified as Blacks. Compared to females, males were more likely to have a higher number of oral sexual partners (OR = 2.10; 95% CI: 1.23, 3.57). Males were also more likely to have earlier oral sexual (b = -2.10; 95% CI: -3.60, -0.60) and vaginal sexual (b = -1.10; 95% CI: -1.69, -0.31) debuts compared to females. Blacks were more likely to have higher number of vaginal sexual partners (OR = 3.38; 95% CI: 1.81, 6.31) and earlier vaginal sex (b = -1.09; 95% CI: -1.78, -0.41) but less likely to have earlier oral sexual debuts compared with Whites (b = 2.67; 95% CI: 1.21, -4.13). Because HPV is associated with several cancers, our findings provide impetus for the development of targeted educational interventions aimed at improving the knowledge of these sexual risk factors, especially among men and across race groups.

摘要

本研究评估了种族和性别是否可以预测与 HPV 相关的已知性风险因素。数据(n=301)来自于 2015 年 9 月 12 日至 13 日在伊利诺伊州麦迪逊市举行的一场飙车比赛的横断面研究。多变量逻辑回归和线性回归模型均用于估计种族、性别和性风险因素之间的关联。约 63%的参与者为男性,65%的参与者为黑人。与女性相比,男性更有可能拥有更多的口腔性伴侣(OR=2.10;95%CI:1.23,3.57)。男性也更有可能更早地发生口腔性行为(b=-2.10;95%CI:-3.60,-0.60)和阴道性行为(b=-1.10;95%CI:-1.69,-0.31)。与白人相比,黑人更有可能拥有更多的阴道性伴侣(OR=3.38;95%CI:1.81,6.31)和更早的阴道性行为(b=-1.09;95%CI:-1.78,-0.41),但更早的口腔性行为较少(b=2.67;95%CI:1.21,-4.13)。由于 HPV 与多种癌症有关,我们的研究结果为制定有针对性的教育干预措施提供了动力,这些措施旨在提高对这些性风险因素的认识,特别是在男性和不同种族群体中。

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