Marshall B J
Division of Gastroenterology, University of Virginia, Charlottesville 22908.
Scand J Gastroenterol Suppl. 1988;146:58-66. doi: 10.3109/00365528809099131.
The Campylobacter pylori story began before the turn of the century, with early works describing 'spirochaetes' in the gastric mucosa of animals. Culture of the organism in 1982 enabled investigators to make sense of the many previous works concerning the microbiology, biochemistry, and histology of the gastric mucosa. Whereas some physicians remain skeptical of C. pylori's pathogenic role, those who have studied the new organism believe it is a major gastrointestinal pathogen and see the possibility of curative therapy for what is now called 'acid peptic disease'.
幽门螺杆菌的故事始于世纪之交之前，早期的研究描述了动物胃黏膜中的“螺旋体”。1982年该生物体的培养使研究人员能够理解此前许多关于胃黏膜微生物学、生物化学和组织学的研究。尽管一些医生对幽门螺杆菌的致病作用仍持怀疑态度，但那些研究这种新生物体的人认为它是一种主要的胃肠道病原体，并看到了对现在所谓的“酸相关性疾病”进行治愈性治疗的可能性。
