Micic S, Hadzi-Djokic J, Dotlic R, Tulic C
Urologic Clinic, Medical Faculty, Belgrade.
Acta Eur Fertil. 1988 May-Jun;19(3):135-7.
A randomised group of 90 men with idiopathic oligoasthenozoospermia was subjected to control study with pentoxifyllin. Pentoxifyllin was given to 51 men 1200 mg daily for 3 months. The other group of 39 infertile men was followed during the same period of time. Significant improvement was observed, in treated group, in percentage of motile sperms and normal shaped sperms after 3 months treatment. This study emphasizes that pentoxifyllin is a relatively good drug for restoring sperm motility and morphology in oligoasthenozoospermic men.
将90名特发性少弱精子症男性随机分组，进行己酮可可碱对照研究。51名男性每天服用1200毫克己酮可可碱，持续3个月。另一组39名不育男性在同一时期接受随访。治疗组在治疗3个月后，活动精子百分比和正常形态精子百分比有显著改善。这项研究强调，己酮可可碱是恢复少弱精子症男性精子活力和形态的相对较好的药物。
