Novák B, László E
Department of Agricultural Chemical Technology, Technical University, Budapest, Hungary.
Acta Microbiol Hung. 1988;35(3):259-68.
The kinetics of cell proliferation of Candida tropicalis synchronized by periodical glucose starvation was examined in a continuous synchronizing fermentor. The length of the deterministic (B) and stochastic (A) phase of the cell cycle was determined by cell density data analysis using the Transition Probability Model. The size distribution of the population shows that the absence of nutrient stops the cells at the beginning of the cell cycle but the succeeding cell divisions are not perfectly synchronized. The reason of this comes from the difference between the generation times of the cells which is the consequence of the different long "A" phases in their cycle.
在连续同步发酵罐中研究了通过周期性葡萄糖饥饿同步化的热带假丝酵母细胞增殖动力学。利用转移概率模型通过细胞密度数据分析确定细胞周期确定性（B）和随机性（A）阶段的时长。群体的大小分布表明，营养物质的缺乏使细胞在细胞周期开始时停滞，但随后的细胞分裂并非完全同步。其原因在于细胞世代时间的差异，这是其周期中不同时长的“A”阶段造成的结果。
