Galvis Jensen N, Vargas Maria V, Robinson Hannah N, Tyan Paul, Gu Alex, Wei Chapman, Janakiram Nikhila, Moawad Gaby
Department of Obstetrics and Gynecology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
JSLS. 2019 Jan-Mar;23(1). doi: 10.4293/JSLS.2018.00089.
Limited research exists on the association between chronic obstructive pulmonary disease (COPD) and morbidity and mortality after laparoscopic hysterectomy. The objective of this study is to examine the following: 1) which demographics and comorbidities are most likely to present concurrently in patients with COPD? 2) Are patients with COPD undergoing laparoscopic hysterectomy at increased risk for development of postoperative complications within 30 days?
Retrospective cohort study using data collected from 2007 to 2016 from the American College of Surgeons National Surgical Quality Improvement Program database. All patients who underwent laparoscopic hysterectomy were identified by Current Procedural Terminology codes and stratified based on COPD status. Univariate and multivariate analyses were completed to define odds ratios for postoperative complications within 30 days of laparoscopic hysterectomy.
This study included 100,518 laparoscopic hysterectomy patients (COPD = 1,130 [1.12%]); (no COPD = 99,388 [98.8%]). Patients with COPD developed more postoperative complications, including pneumonia, reintubation, renal insufficiency, and sepsis. COPD was identified as an independent risk factor for pneumonia (OR, 4.098; 95% CI, 2.222-7.519) and reintubation (OR, 4.348; 95% CI, 2.387-7.937). Patients with COPD had extended length of hospital stay.
Patients with COPD who undergo laparoscopic hysterectomy have increased risk of experiencing postoperative pneumonia, reintubation, renal insufficiency, and sepsis. Overall, postoperative complication rates remain low, but gynecologists should consider the pulmonary disease status of patients when assessing preoperative risk.
关于慢性阻塞性肺疾病(COPD)与腹腔镜子宫切除术后发病率和死亡率之间的关联,现有研究有限。本研究的目的是探讨以下内容:1)哪些人口统计学特征和合并症最有可能在COPD患者中同时出现?2)接受腹腔镜子宫切除术的COPD患者在30天内发生术后并发症的风险是否增加?
采用回顾性队列研究,使用从2007年至2016年美国外科医师学会国家外科质量改进计划数据库收集的数据。通过当前手术操作术语代码识别所有接受腹腔镜子宫切除术的患者,并根据COPD状态进行分层。完成单因素和多因素分析,以确定腹腔镜子宫切除术后30天内术后并发症的比值比。
本研究纳入了100,518例腹腔镜子宫切除术患者(COPD = 1,130例[1.12%]);(无COPD = 99,388例[98.8%])。COPD患者发生更多术后并发症,包括肺炎、再次插管、肾功能不全和败血症。COPD被确定为肺炎(OR,4.098;95%CI,2.222 - 7.519)和再次插管(OR,4.348;95%CI,2.387 - 7.937)的独立危险因素。COPD患者住院时间延长。
接受腹腔镜子宫切除术的COPD患者发生术后肺炎、再次插管、肾功能不全和败血症的风险增加。总体而言,术后并发症发生率仍然较低,但妇科医生在评估术前风险时应考虑患者的肺部疾病状况。