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认知和年龄在被诊断患有痴呆症的人群中的种族差异:两家大型精神保健机构电子健康记录的研究。

Ethnic differences in cognition and age in people diagnosed with dementia: A study of electronic health records in two large mental healthcare providers.

机构信息

UCL Division of Psychiatry, London, UK.

Camden and Islington NHS Foundation Trust, St. Pancras Hospital, London, UK.

出版信息

Int J Geriatr Psychiatry. 2019 Mar;34(3):504-510. doi: 10.1002/gps.5046. Epub 2019 Jan 24.

DOI:10.1002/gps.5046
PMID:30675737
Abstract

OBJECTIVES

Qualitative studies suggest that people from UK minority ethnic groups with dementia access health services later in the illness than white UK-born elders, but there are no large quantitative studies investigating this. We aimed to investigate interethnic differences in cognitive scores and age at dementia diagnosis.

METHODS

We used the Clinical Record Interactive Search (CRIS) applied to the electronic health records of two London mental health trusts to identify patients diagnosed with dementia between 2008 and 2016. We meta-analysed mean Mini Mental State Examination (MMSE) and mean age at the time of diagnosis across trusts for the most common ethnic groups, and used linear regression models to test these associations before and after adjustment for age, sex, index of multiple deprivation, and marital status. We also compared percentage of referrals for each ethnic group with catchment census distributions.

RESULTS

Compared with white patients (N = 9380), unadjusted mean MMSE scores were lower in Asian (-1.25; 95% CI -1.79, -0.71; N = 642) and black patients (-1.82, 95% CI -2.13, -1.52; N = 2008) as was mean age at diagnosis (Asian patients: -4.27 (-4.92, -3.61); black patients -3.70 (-4.13, -3.27) years). These differences persisted after adjustment. In general, ethnic group distributions in referrals did not differ substantially from those expected in the catchments.

CONCLUSIONS

People from black and Asian groups were younger at dementia diagnosis and had lower MMSE scores than white referrals.

摘要

目的

定性研究表明,与英国出生的白人老年人相比,英国少数族裔痴呆患者在疾病后期才会使用医疗服务,但目前尚无大规模的定量研究来调查这一现象。本研究旨在调查不同族裔之间认知评分和痴呆诊断年龄的差异。

方法

我们使用伦敦两家心理健康信托机构的电子健康记录中的临床记录交互式搜索(CRIS)来识别 2008 年至 2016 年间被诊断为痴呆症的患者。我们对各信托机构最常见族裔的平均简易精神状态检查(MMSE)评分和诊断时的平均年龄进行荟萃分析,并使用线性回归模型在调整年龄、性别、多重剥夺指数和婚姻状况后检验这些关联。我们还比较了各族裔的转诊比例与普查人口分布的差异。

结果

与白人患者(N=9380)相比,未经调整的 MMSE 评分在亚裔患者中较低(-1.25;95%CI:-1.79,-0.71;N=642),在黑人患者中较低(-1.82;95%CI:-2.13,-1.52;N=2008),诊断时的平均年龄也较低(亚裔患者:-4.27;95%CI:-4.92,-3.61;黑人患者:-3.70;95%CI:-4.13,-3.27)。调整后这些差异仍然存在。总体而言,转诊患者的族裔分布与普查人口分布基本一致。

结论

与白人转诊患者相比,黑人和亚裔群体的痴呆诊断年龄更小,MMSE 评分更低。

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