Bohnstedt M, Fox P J, Kohatsu N D
California Department of Health Services, Sacramento, U.S.A.
J Clin Epidemiol. 1994 Dec;47(12):1381-7. doi: 10.1016/0895-4356(94)90082-5.
Data on 1888 patients seen at Alzheimer's Disease Diagnostic and Treatment Centers in California were used to examine possible differences in Mini-Mental State Examination (MMSE) results for different racial-ethnic groups. White patients had scores less indicative of dementia than Black and Hispanic patients using the standard 23 cutting point on the MMSE. However, there were no differences among these groups in the percentages clinically diagnosed as demented. The difference in the percentage of Whites vs Blacks and Hispanics categorized as demented by the MMSE was not accounted for by education, occupation, age, sex, or other variables tested, even though these variables were correlated with MMSE scores. Our data suggest that clinicians should consider MMSE scores for Black and Hispanic patients an underestimate of their cognitive capabilities relative to that of White patients.
对在加利福尼亚州阿尔茨海默病诊断与治疗中心就诊的1888名患者的数据进行分析，以检验不同种族-族裔群体在简易精神状态检查表（MMSE）结果上可能存在的差异。使用MMSE标准的23分切点时，白人患者的得分比黑人和西班牙裔患者更不提示痴呆。然而，这些群体中临床诊断为痴呆的百分比并无差异。尽管这些变量与MMSE得分相关，但白人、黑人和西班牙裔被MMSE分类为痴呆的百分比差异并不能由教育程度、职业、年龄、性别或其他测试变量来解释。我们的数据表明，临床医生应考虑到相对于白人患者，MMSE得分可能低估了黑人和西班牙裔患者的认知能力。
