Binkhorst C D, Nygaard P, Loones L H
Am J Ophthalmol. 1978 May;85(5 Pt 1):597-605. doi: 10.1016/s0002-9394(14)77090-4.
Specular microscopy helps to estimate the viability of the corneal endothelium long before clinical signs of decompensation occur. Therefore, specular microscopy is useful for the selection of eyes for lens implantation in general; for the prognosis of the eye with a lens implant; and for the evaluation of the method of cataract surgery, of lens implantation techniques, and possibly of lens design, material, and manufacturing. A long-term study of intracapsular and extracapsular pseudophakic eyes revealed that the intracapsular pseudophakic eyes had significantly less endothelial cells, which could partly be explained by toxicity of the Supramid used as loop material, but mostly by assuming continuing endothelial disintegration in the intracapsular eyes. In 41 patients our extracapsular technique caused an average cell loss of only 6.7%.
早在角膜失代偿的临床体征出现之前，镜面显微镜检查有助于评估角膜内皮细胞的活力。因此，一般来说，镜面显微镜检查对于选择适合植入人工晶状体的眼睛、评估植入人工晶状体的眼睛的预后、以及评估白内障手术方法、人工晶状体植入技术以及可能的人工晶状体设计、材料和制造都很有用。一项对囊内和囊外人工晶状体眼的长期研究表明，囊内人工晶状体眼的内皮细胞明显较少，部分原因可解释为用作袢材料的苏普拉明的毒性，但主要是由于假定囊内眼的内皮细胞持续崩解。在41例患者中，我们的囊外技术导致的平均细胞损失仅为6.7%。
