May D R, Freedland R J, Charles S, Wang C, Bakos J
Br J Ophthalmol. 1983 Dec;67(12):808-13. doi: 10.1136/bjo.67.12.808.
The anterior chambers of 27 rabbit eyes were perfused at constant pressure with room temperature (25 degrees C) or cooled (11 degrees C) balanced salt solution at constant flow rates of 4.8 ml/min or 8.5 ml/min. Intraocular temperature changes in the anterior chamber, anterior vitreous, mid vitreous, and posterior vitreous and on the retina surface were monitored with an intraocular thermocouple probe. Perfusion of the anterior chamber of the pigmented rabbit eye with cooled fluid significantly reduced the temperature of the anterior chamber and anterior vitreous and even that of the retina. Both an increase in the rate of perfusion and a lowering of the perfusion temperature enhanced the cooling effect. The observed decrease in temperatures returned to approximately normal 4 minutes following the cessation of perfusion.
用室温（25摄氏度）或冷却（11摄氏度）的平衡盐溶液，以4.8毫升/分钟或8.5毫升/分钟的恒定流速对27只兔眼的前房进行恒压灌注。使用眼内热电偶探头监测前房、眼前玻璃体、玻璃体中部、眼后玻璃体以及视网膜表面的眼内温度变化。用冷却的液体灌注有色兔眼的前房，可显著降低前房和眼前玻璃体的温度，甚至降低视网膜的温度。灌注速率的增加和灌注温度的降低均增强了冷却效果。灌注停止4分钟后，观察到的温度下降恢复到大致正常水平。
