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澳大利亚托雷斯海峡群岛的类鼻疽病:病原体、宿主和环境之间的精彩相互作用。

Melioidosis in the Torres Strait Islands, Australia: Exquisite Interplay between Pathogen, Host, and Environment.

机构信息

Torres and Cape Hospital and Health Service, Thursday Island, Australia.

James Cook University, Cairns, Australia.

出版信息

Am J Trop Med Hyg. 2019 Mar;100(3):517-521. doi: 10.4269/ajtmh.18-0806.

DOI:10.4269/ajtmh.18-0806
PMID:30675834
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6402897/
Abstract

, a bacterium that lives in the soil of the tropics, causes the disease melioidosis. This retrospective study investigated the temporospatial epidemiology of the 49 laboratory-confirmed melioidosis cases in the Torres Straits Islands of tropical Australia between 1997 and 2017. An identifiable risk factor for the disease was present in 43/49 (88%) cases and in 35/36 (97%) cases with complete clinical data. The mean incidence of melioidosis varied across the region, from 0/100,000 persons/year in the Eastern Island Cluster to 116.1/100,000 persons/year in the Near Western Island Cluster. An environmental suitability score for the growth of -constructed using the rainfall, vegetation, and soil type on each island-correlated with disease incidence (Spearman's rho 0.51; = 0.035). Melioidosis is an opportunistic disease that occurs in patients with specific risk factors, but its incidence is also strongly influenced by environmental factors that favor the growth of the causative organism.

摘要

一种生活在热带土壤中的细菌,引起疾病类鼻疽。本回顾性研究调查了 1997 年至 2017 年间澳大利亚热带托雷斯海峡群岛的 49 例实验室确诊类鼻疽病例的时空流行病学。43/49 例(88%)和 35/36 例(97%)有完整临床数据的病例存在可识别的危险因素。该疾病的平均发病率在该地区各不相同,从东部岛屿群的 0/100,000 人/年到近西部岛屿群的 116.1/100,000 人/年。使用每个岛屿的降雨、植被和土壤类型构建的生长环境适宜性评分与疾病发病率相关(Spearman's rho 0.51; = 0.035)。类鼻疽是一种机会性疾病,发生在具有特定危险因素的患者中,但它的发病率也受到有利于病原体生长的环境因素的强烈影响。

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本文引用的文献

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Melioidosis: An Australian Perspective.类鼻疽:澳大利亚视角
Trop Med Infect Dis. 2018 Mar 1;3(1):27. doi: 10.3390/tropicalmed3010027.
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Case Report: Fatal Pediatric Melioidosis Despite Optimal Intensive Care.病例报告:尽管进行了最佳重症监护,小儿类鼻疽仍 fatal(此处“fatal”有误,结合语境推测可能是“致死”之意,整句应是“尽管进行了最佳重症监护,小儿类鼻疽仍致死” ) 。
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