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乳糜泻与妇产科疾病:我们目前的进展如何?

Coeliac disease and obstetric and gynaecological disorders: where are we now?

作者信息

Schiepatti Annalisa, Sprio Elisa, Sanders David S, Lovati Elisabetta, Biagi Federico

机构信息

First Department of Internal Medicine, IRCCS Policlinico San Matteo, University of Pavia, Italy.

Academic Department of Gastroenterology, Royal Hallamshire Hospital, University of Sheffield, Sheffield, UK.

出版信息

Eur J Gastroenterol Hepatol. 2019 Apr;31(4):425-433. doi: 10.1097/MEG.0000000000001361.

Abstract

Coeliac disease (CD) is a chronic gluten-dependent enteropathy very common in the general population and characterized by an extremely heterogeneous clinical picture. Although its prevalence is growing worldwide, case-finding strategy remains the mainstay to diagnosis. Thus, correct identification of high-risk categories of patients who need to be tested for CD is an essential part of medical knowledge to a large number of specialists and primary care providers. In this regard, although CD might have a serious effect on women's reproductive health, a widespread consensus is lacking on which categories of obstetric and gynaecological disorders should be tested for CD. The aim of this review is to critically summarize the current literature relevant to CD and obstetric and gynaecological disorders and to provide practical proposals that may be helpful to clinicians involved in the management of these patients.

摘要

乳糜泻(CD)是一种常见的慢性麸质依赖性肠病,临床表现极为多样。尽管其在全球的患病率呈上升趋势,但病例发现策略仍是诊断的主要手段。因此,正确识别需要进行CD检测的高危患者类别,是众多专科医生和初级保健提供者医学知识的重要组成部分。在这方面,虽然CD可能对女性生殖健康有严重影响,但对于哪些产科和妇科疾病应进行CD检测,目前尚未达成广泛共识。本综述的目的是批判性地总结当前与CD以及产科和妇科疾病相关的文献,并提供实用建议,以帮助参与这些患者管理的临床医生。

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